Vitamin D serum levels and allergic rhinitis

M. Wjst, E. Hyppönen

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

In addition to its role in the regulation of calcium metabolism, vitamin D has a number of immunological effects. Several studies in children found an effect of oral supplementation on allergic sensitization but so far there are no population-based studies of vitamin D serum levels. We therefore examined 25(OH)-D3 status in 18 224 adults of the Third National Health and Nutrition Examination Survey. There was no effect on sensitization to a single allergen while the prevalence of allergic rhinitis increased across quartile groups of current vitamin D serum levels. The association could be due to unrecognized confounding, however, could also point towards an altered metabolism or an increased sensitivity to vitamin D in allergic patients.

Original languageEnglish
Pages (from-to)1085-1086
Number of pages2
JournalAllergy: European Journal of Allergy and Clinical Immunology
Volume62
Issue number9
DOIs
Publication statusPublished - 1 Sep 2007
Externally publishedYes

Keywords

  • Allergic rhinitis
  • Confounder
  • Sensitization
  • Vitamin D

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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