Two pregnancies after simultaneous pancreas–kidney transplantation: A case report

Fadak Mohammadi, Stephen McDonald, Erin Clark, Shilpanjali Jesudason

Research output: Contribution to journalArticle

Abstract

Simultaneous kidney–pancreas transplantation can successfully restore fertility in women with type 1 diabetes mellitus and kidney failure. There have been few cases of pregnancy after simultaneous kidney–pancreas transplantation, and a second pregnancy is rare. We report a case of two live births in rapid succession in a simultaneous kidney–pancreas transplantation recipient, complicated by pre-eclampsia but with excellent fetal and graft outcomes. The first pregnancy was achieved with IVF, while the second was achieved naturally. Simultaneous kidney–pancreas transplantation with stable pre-pregnancy graft function enabled this patient to achieve successful pregnancy. However, both pregnancies were complicated by transient renal graft dysfunction and pre-eclampsia precipitating pre-term birth.

LanguageEnglish
JournalObstetric Medicine
DOIs
Publication statusAccepted/In press - 2018

Keywords

  • High-risk pregnancy
  • kidney
  • pancreas
  • pre-eclampsia
  • transplantation

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

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title = "Two pregnancies after simultaneous pancreas–kidney transplantation: A case report",
abstract = "Simultaneous kidney–pancreas transplantation can successfully restore fertility in women with type 1 diabetes mellitus and kidney failure. There have been few cases of pregnancy after simultaneous kidney–pancreas transplantation, and a second pregnancy is rare. We report a case of two live births in rapid succession in a simultaneous kidney–pancreas transplantation recipient, complicated by pre-eclampsia but with excellent fetal and graft outcomes. The first pregnancy was achieved with IVF, while the second was achieved naturally. Simultaneous kidney–pancreas transplantation with stable pre-pregnancy graft function enabled this patient to achieve successful pregnancy. However, both pregnancies were complicated by transient renal graft dysfunction and pre-eclampsia precipitating pre-term birth.",
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AU - Jesudason, Shilpanjali

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AB - Simultaneous kidney–pancreas transplantation can successfully restore fertility in women with type 1 diabetes mellitus and kidney failure. There have been few cases of pregnancy after simultaneous kidney–pancreas transplantation, and a second pregnancy is rare. We report a case of two live births in rapid succession in a simultaneous kidney–pancreas transplantation recipient, complicated by pre-eclampsia but with excellent fetal and graft outcomes. The first pregnancy was achieved with IVF, while the second was achieved naturally. Simultaneous kidney–pancreas transplantation with stable pre-pregnancy graft function enabled this patient to achieve successful pregnancy. However, both pregnancies were complicated by transient renal graft dysfunction and pre-eclampsia precipitating pre-term birth.

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KW - kidney

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KW - pre-eclampsia

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