Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015: findings from the Global Burden of Disease 2015 study

Charbel El Bcheraoui, Haidong Wang, Raghid Charara, Ibrahim Khalil, Maziar Moradi-Lakeh, Ashkan Afshin, Michael Collison, Farah Daoud, Adrienne Chew, Kristopher J. Krohn, Austin Carter, Kyle J. Foreman, Fei He, Nicholas J. Kassebaum, Michael Kutz, Mojde Mirarefin, Grant Nguyen, Naris Silpakit, Amber Sligar, Amanuel A. Abajobir & 31 others Kalkidan H. Abate, Kaja M. Abbas, Foad Abd-Allah, Semaw F. Abera, Kelemework Adane, Arnav Agarwal, Aliasghar Ahmadkiadaliri, Alireza Ahmadi, Muktar B. Ahmed, Faris H. Al Lami, Khurshid Alam, Deena Alasfoor, Reza Alizadeh-Navaei, Fatma Al-Maskari, Rajaa Al-Raddadi, Khalid A. Altirkawi, Nelson Alvis-Guzman, Walid Ammar, Nahla Anber, Carl Abelardo T. Antonio, Palwasha Anwari, Hamid Asayesh, Rana J. Asghar, Tesfay Mehari Atey, Euripide F.G.A. Avokpaho, Tadesse Awokeayele, Peter Azzopardi, Umar Bacha, Aleksandra Barac, Till Bärnighausen, GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

LanguageEnglish
Pages123-136
Number of pages14
JournalInternational Journal of Public Health
Volume63
DOIs
Publication statusPublished - 1 May 2018

Keywords

  • Burden of disease
  • Eastern Mediterranean Region
  • HIV
  • HIV mortality

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

El Bcheraoui, C., Wang, H., Charara, R., Khalil, I., Moradi-Lakeh, M., Afshin, A., ... GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators (2018). Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015: findings from the Global Burden of Disease 2015 study. International Journal of Public Health, 63, 123-136. https://doi.org/10.1007/s00038-017-1023-0
El Bcheraoui, Charbel ; Wang, Haidong ; Charara, Raghid ; Khalil, Ibrahim ; Moradi-Lakeh, Maziar ; Afshin, Ashkan ; Collison, Michael ; Daoud, Farah ; Chew, Adrienne ; Krohn, Kristopher J. ; Carter, Austin ; Foreman, Kyle J. ; He, Fei ; Kassebaum, Nicholas J. ; Kutz, Michael ; Mirarefin, Mojde ; Nguyen, Grant ; Silpakit, Naris ; Sligar, Amber ; Abajobir, Amanuel A. ; Abate, Kalkidan H. ; Abbas, Kaja M. ; Abd-Allah, Foad ; Abera, Semaw F. ; Adane, Kelemework ; Agarwal, Arnav ; Ahmadkiadaliri, Aliasghar ; Ahmadi, Alireza ; Ahmed, Muktar B. ; Al Lami, Faris H. ; Alam, Khurshid ; Alasfoor, Deena ; Alizadeh-Navaei, Reza ; Al-Maskari, Fatma ; Al-Raddadi, Rajaa ; Altirkawi, Khalid A. ; Alvis-Guzman, Nelson ; Ammar, Walid ; Anber, Nahla ; Antonio, Carl Abelardo T. ; Anwari, Palwasha ; Asayesh, Hamid ; Asghar, Rana J. ; Atey, Tesfay Mehari ; Avokpaho, Euripide F.G.A. ; Awokeayele, Tadesse ; Azzopardi, Peter ; Bacha, Umar ; Barac, Aleksandra ; Bärnighausen, Till ; GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators. / Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015 : findings from the Global Burden of Disease 2015 study. In: International Journal of Public Health. 2018 ; Vol. 63. pp. 123-136.
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abstract = "Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43{\%} increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.",
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El Bcheraoui, C, Wang, H, Charara, R, Khalil, I, Moradi-Lakeh, M, Afshin, A, Collison, M, Daoud, F, Chew, A, Krohn, KJ, Carter, A, Foreman, KJ, He, F, Kassebaum, NJ, Kutz, M, Mirarefin, M, Nguyen, G, Silpakit, N, Sligar, A, Abajobir, AA, Abate, KH, Abbas, KM, Abd-Allah, F, Abera, SF, Adane, K, Agarwal, A, Ahmadkiadaliri, A, Ahmadi, A, Ahmed, MB, Al Lami, FH, Alam, K, Alasfoor, D, Alizadeh-Navaei, R, Al-Maskari, F, Al-Raddadi, R, Altirkawi, KA, Alvis-Guzman, N, Ammar, W, Anber, N, Antonio, CAT, Anwari, P, Asayesh, H, Asghar, RJ, Atey, TM, Avokpaho, EFGA, Awokeayele, T, Azzopardi, P, Bacha, U, Barac, A, Bärnighausen, T & GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators 2018, 'Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015: findings from the Global Burden of Disease 2015 study', International Journal of Public Health, vol. 63, pp. 123-136. https://doi.org/10.1007/s00038-017-1023-0

Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015 : findings from the Global Burden of Disease 2015 study. / El Bcheraoui, Charbel; Wang, Haidong; Charara, Raghid; Khalil, Ibrahim; Moradi-Lakeh, Maziar; Afshin, Ashkan; Collison, Michael; Daoud, Farah; Chew, Adrienne; Krohn, Kristopher J.; Carter, Austin; Foreman, Kyle J.; He, Fei; Kassebaum, Nicholas J.; Kutz, Michael; Mirarefin, Mojde; Nguyen, Grant; Silpakit, Naris; Sligar, Amber; Abajobir, Amanuel A.; Abate, Kalkidan H.; Abbas, Kaja M.; Abd-Allah, Foad; Abera, Semaw F.; Adane, Kelemework; Agarwal, Arnav; Ahmadkiadaliri, Aliasghar; Ahmadi, Alireza; Ahmed, Muktar B.; Al Lami, Faris H.; Alam, Khurshid; Alasfoor, Deena; Alizadeh-Navaei, Reza; Al-Maskari, Fatma; Al-Raddadi, Rajaa; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Ammar, Walid; Anber, Nahla; Antonio, Carl Abelardo T.; Anwari, Palwasha; Asayesh, Hamid; Asghar, Rana J.; Atey, Tesfay Mehari; Avokpaho, Euripide F.G.A.; Awokeayele, Tadesse; Azzopardi, Peter; Bacha, Umar; Barac, Aleksandra; Bärnighausen, Till; GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators.

In: International Journal of Public Health, Vol. 63, 01.05.2018, p. 123-136.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015

T2 - International Journal of Public Health

AU - El Bcheraoui, Charbel

AU - Wang, Haidong

AU - Charara, Raghid

AU - Khalil, Ibrahim

AU - Moradi-Lakeh, Maziar

AU - Afshin, Ashkan

AU - Collison, Michael

AU - Daoud, Farah

AU - Chew, Adrienne

AU - Krohn, Kristopher J.

AU - Carter, Austin

AU - Foreman, Kyle J.

AU - He, Fei

AU - Kassebaum, Nicholas J.

AU - Kutz, Michael

AU - Mirarefin, Mojde

AU - Nguyen, Grant

AU - Silpakit, Naris

AU - Sligar, Amber

AU - Abajobir, Amanuel A.

AU - Abate, Kalkidan H.

AU - Abbas, Kaja M.

AU - Abd-Allah, Foad

AU - Abera, Semaw F.

AU - Adane, Kelemework

AU - Agarwal, Arnav

AU - Ahmadkiadaliri, Aliasghar

AU - Ahmadi, Alireza

AU - Ahmed, Muktar B.

AU - Al Lami, Faris H.

AU - Alam, Khurshid

AU - Alasfoor, Deena

AU - Alizadeh-Navaei, Reza

AU - Al-Maskari, Fatma

AU - Al-Raddadi, Rajaa

AU - Altirkawi, Khalid A.

AU - Alvis-Guzman, Nelson

AU - Ammar, Walid

AU - Anber, Nahla

AU - Antonio, Carl Abelardo T.

AU - Anwari, Palwasha

AU - Asayesh, Hamid

AU - Asghar, Rana J.

AU - Atey, Tesfay Mehari

AU - Avokpaho, Euripide F.G.A.

AU - Awokeayele, Tadesse

AU - Azzopardi, Peter

AU - Bacha, Umar

AU - Barac, Aleksandra

AU - Bärnighausen, Till

AU - GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

AB - Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

KW - Burden of disease

KW - Eastern Mediterranean Region

KW - HIV

KW - HIV mortality

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U2 - 10.1007/s00038-017-1023-0

DO - 10.1007/s00038-017-1023-0

M3 - Article

VL - 63

SP - 123

EP - 136

JO - International Journal of Public Health

JF - International Journal of Public Health

SN - 1661-8556

ER -