Transition between different renal replacement modalities: Gaps in knowledge and care—the integrated research initiative

Christopher Chan, Gill Combes, Simon Davies, Fred Finkelstein, Catherine Firanek, Rafael Gomez, Kitty J. Jager, Vivek Jha George, David W. Johnson, Mark Lambie, Magdalena Madero, Ikuto Masakane, Stephen McDonald, Madhukar Misra, Sandip Mitra, Thyago Moraes, Annie Claire Nadeau-Fredette, Purna Mukhopadhyay, Jeff Perl, Ronald PisoniBruce Robinson, Dong Ryeol Ryu, Rajiv Saran, James Sloand, Nidhi Sukul, Allison Tong, Cheuk Chun Szeto, Wim Van Biesen

Research output: Contribution to journalReview articlepeer-review

11 Citations (Scopus)


Patients with end-stage kidney disease (ESKD) have different options to replace the function of their failing kidneys. The “inte-grated care” model considers treatment pathways rather than individual renal replacement therapy (RRT) techniques. In such a paradigm, the optimal strategy to plan and enact transitions between the different modalities is very relevant, but so far, only limited data on transitions have been published. Perspectives of patients, caregivers, and health professionals on the process of transitioning are even less well documented. Available literature suggests that poor coordination causes significant morbidity and mortality. This review briefly provides the background, development, and scope of the INTErnational Group Research Assessing Transition Effects in Dialysis (INTEGRATED) initiative. We summarize the literature on the transition between different RRT modalities. Further, we present an international research plan to quantify the epidemiology and to assess the qualitative aspects of transition between different modalities.

Original languageEnglish
Pages (from-to)4-12
Number of pages9
JournalPeritoneal Dialysis International
Issue number1
Publication statusPublished or Issued - 1 Jan 2019


  • Barriers
  • Collaboration
  • Integrated care
  • International
  • Patient beliefs
  • Planned/unplanned transitions

ASJC Scopus subject areas

  • Nephrology

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