Transdermal fentanyl and its use in ovine surgery

Chris Christou, Rema A. Oliver, John Rawlinson, William R. Walsh

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Fentanyl delivered via a transdermal patch has the potential to decrease the need for post-operative handling of sheep undergoing surgical procedures. Two studies were performed to test: (1) the ideal timing for the application of pre-emptive analgesic patches and (2) the efficacy of a 2 μg/kg/h dose, as extrapolated from other species. The first study had sheep divided into two groups. Group 1 had a fentanyl patch applied for 24 h prior to a patch change and group 2 had a fentanyl patch applied 72 h prior to a change.The second study applied the results obtained in the first and tested the efficacy of 2 μg/kg/h as an effective dose in an orthopaedic surgical environment.Results indicated that the ideal time for pre-emptive fentanyl patch administration is 24-36 h prior to surgery and that 2 μg/kg/h is an effective minimum therapeutic dose rate for the use of fentanyl as an analgesic in an orthopaedic surgical environment.

Original languageEnglish
Pages (from-to)252-256
Number of pages5
JournalResearch in Veterinary Science
Volume100
DOIs
Publication statusPublished - 1 Jun 2015

Keywords

  • Analgesia
  • Fentanyl
  • Ovine
  • Pre-emptive
  • Sheep

ASJC Scopus subject areas

  • veterinary(all)
  • Medicine(all)

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