The role of expectant management for couples with unexplained infertility

N. M. Van Den Boogaard, Fulco Van Der Veen, Ben Willem Mol

Research output: Chapter in Book/Report/Conference proceedingChapter


In couples with unexplained infertility, no convincing evidence is available that treatment with intra uterine insemination (IUI) with or without ovarian stimulation (OS) or in vitro fertilisation (IVF) improves pregnancy rates compared to expectant management. Expectant management in couples with unexplained infertility leads to live birth rates varying between 10 and 50 % per year, depending on their prognosis, based on female age, duration of subfertility and the outcomes of the fertility workup. Optimal implementation of expectant management in couples with good prospects of natural conception can prevent unnecessary treatments, complications and costs.

Title of host publicationUnexplained Infertility
Subtitle of host publicationPathophysiology, Evaluation and Treatment
PublisherSpringer New York
Number of pages3
ISBN (Electronic)9781493921409
ISBN (Print)9781493921393
Publication statusPublished - 1 Jan 2015
Externally publishedYes


  • Expectant management
  • Intra uterine insemination
  • Prognostic models
  • Tailored expectant management
  • Unexplained infertility

ASJC Scopus subject areas

  • Health Professions(all)
  • Medicine(all)

Cite this

Van Den Boogaard, N. M., Van Der Veen, F., & Mol, B. W. (2015). The role of expectant management for couples with unexplained infertility. In Unexplained Infertility: Pathophysiology, Evaluation and Treatment (pp. 241-243). Springer New York.