The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific

Andrey N. Shkoporov; Adam G. Clooney; Thomas D.S. Sutton; Feargal Ryan; Karen M. Daly; James A. Nolan; Siobhan A. McDonnell; Ekaterina V. Khokhlova; Lorraine A. Draper; Amanda Forde; Emma Guerin; Vimalkumar Velayudhan; R. Paul Ross; Colin Hill

doi:10.1016/j.chom.2019.09.009

The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific

Andrey N. Shkoporov, Adam G. Clooney, Thomas D.S. Sutton, Feargal Ryan, Karen M. Daly, James A. Nolan, Siobhan A. McDonnell, Ekaterina V. Khokhlova, Lorraine A. Draper, Amanda Forde, Emma Guerin, Vimalkumar Velayudhan, R. Paul Ross, Colin Hill

Computational And Systems Biology

Research output: Contribution to journal › Article

16 Citations (Scopus)

Abstract

Shkoporov et al. demonstrate high individual specificity and temporal stability of the human gut virome. They describe a numerically prevalent and persisting fraction of the viral community, termed persistent personal virome (PPV). The PPV consists mainly of virulent bacteriophages predicted to target major taxonomic groups of gut bacteria.

Language	English
Pages	527-541.e5
Journal	Cell Host and Microbe
Volume	26
Issue number	4
DOIs	10.1016/j.chom.2019.09.009
Publication status	Published - 9 Oct 2019

Keywords

CRISPR
Microviridae
bacteriophages
crAss-like phages
crAssphage
human microbiome
longitudinal study
persistent personal virome
phageome
virome

ASJC Scopus subject areas

Parasitology
Microbiology
Virology

Cite this

Shkoporov, A. N., Clooney, A. G., Sutton, T. D. S., Ryan, F., Daly, K. M., Nolan, J. A., ... Hill, C. (2019). The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific. Cell Host and Microbe, 26(4), 527-541.e5. https://doi.org/10.1016/j.chom.2019.09.009

Shkoporov, Andrey N. ; Clooney, Adam G. ; Sutton, Thomas D.S. ; Ryan, Feargal ; Daly, Karen M. ; Nolan, James A. ; McDonnell, Siobhan A. ; Khokhlova, Ekaterina V. ; Draper, Lorraine A. ; Forde, Amanda ; Guerin, Emma ; Velayudhan, Vimalkumar ; Ross, R. Paul ; Hill, Colin. / The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific. In: Cell Host and Microbe. 2019 ; Vol. 26, No. 4. pp. 527-541.e5.

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The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific. / Shkoporov, Andrey N.; Clooney, Adam G.; Sutton, Thomas D.S.; Ryan, Feargal; Daly, Karen M.; Nolan, James A.; McDonnell, Siobhan A.; Khokhlova, Ekaterina V.; Draper, Lorraine A.; Forde, Amanda; Guerin, Emma; Velayudhan, Vimalkumar; Ross, R. Paul; Hill, Colin.

In: Cell Host and Microbe, Vol. 26, No. 4, 09.10.2019, p. 527-541.e5.

Research output: Contribution to journal › Article

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Access to Document

10.1016/j.chom.2019.09.009

Link to publication in Scopus