The histological and ultrastructural features of the epiphyseal plate in morquio type a syndrome (mucopolysaccharidosis type IVA)

John McClure, P. S. Smith, G. Sorby-Adamsi, J. Hopwood

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Tissue from the epiphyseal plate of a patient with Morquio type A syndrome (mucopolysaccharidosis type IVA) was studied by undecalcified histological and electron microscopical techniques. Cartilage cells in the plate were vacuolated to a variable degree. The orderly proliferating structure of the epiphyseal plate was absent and calcification was markedly reduced. The related bone tissue was morphologically normal although reduced in quantity.

LanguageEnglish
Pages217-221
Number of pages5
JournalPathology
Volume18
Issue number2
DOIs
Publication statusPublished - 1 Jan 1986
Externally publishedYes

Keywords

  • Chondrocyte vacuolation
  • Morquio type A syndrome
  • Reduced calcification

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

McClure, John ; Smith, P. S. ; Sorby-Adamsi, G. ; Hopwood, J. / The histological and ultrastructural features of the epiphyseal plate in morquio type a syndrome (mucopolysaccharidosis type IVA). In: Pathology. 1986 ; Vol. 18, No. 2. pp. 217-221.
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The histological and ultrastructural features of the epiphyseal plate in morquio type a syndrome (mucopolysaccharidosis type IVA). / McClure, John; Smith, P. S.; Sorby-Adamsi, G.; Hopwood, J.

In: Pathology, Vol. 18, No. 2, 01.01.1986, p. 217-221.

Research output: Contribution to journalArticle

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