The 1984 Tasmanian insulin treated diabetes mellitus prevalence cohort: An eight and a half year mortality follow-up investigation

M. D. Riley, D. J. McCarty, D. J. Couper, A. R.G. Humphrey, T. Dwyer, P. Z. Zimmet

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Total mortality and underlying cause of death were examined in a population-based prevalence cohort (n = 1232) of Tasmanians with insulin-treated diabetes mellitus. Eight and a half years after the establishment of the registry, the cause of death based on death certificate information was determined for the overall cohort and for three clasification groups of insulin-treated diabetes: Group A - childhood-onset IDDM cases; Group B - adult-onset IDDM cases; and Group C - adult-onset insulin-treated NIDDM cases. A total of 378 deaths occurred, providing an overall SMR of 2.2 (95% CI 2.0-2.4) compared to the Tasmanian population. Diabetic females experienced a higher SMR (2.6, 95% CI 2.3-3.0) than diabetic males (1.9, 95% CI 1.6-2.2). The all-cause SMRs for the diabetic classification groups were 4.6 (95% CI 3.4-6.1) in Group A, 1.8 (95% CI 1.5-2.1) in Group B, and 2.2 (95% CI 1.9-2.6) in Group C. After adjusting for age, gender and duration of diabetes, the mortality in Group C was significantly higher compared to Group B (odds ratio 1.6, 95% CI 1.2-2.3). This study indicates that people with childhood-onset IDDM experience 4.6 times the death rate compared to the Tasmanian population and that the excess mortality is most pronounced in females.

LanguageEnglish
Pages27-35
Number of pages9
JournalDiabetes Research and Clinical Practice
Volume29
Issue number1
DOIs
Publication statusPublished - 1995
Externally publishedYes

Keywords

  • Epidemiology
  • IDDM
  • Mortality
  • NIDDM

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Riley, M. D. ; McCarty, D. J. ; Couper, D. J. ; Humphrey, A. R.G. ; Dwyer, T. ; Zimmet, P. Z. / The 1984 Tasmanian insulin treated diabetes mellitus prevalence cohort : An eight and a half year mortality follow-up investigation. In: Diabetes Research and Clinical Practice. 1995 ; Vol. 29, No. 1. pp. 27-35.
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The 1984 Tasmanian insulin treated diabetes mellitus prevalence cohort : An eight and a half year mortality follow-up investigation. / Riley, M. D.; McCarty, D. J.; Couper, D. J.; Humphrey, A. R.G.; Dwyer, T.; Zimmet, P. Z.

In: Diabetes Research and Clinical Practice, Vol. 29, No. 1, 1995, p. 27-35.

Research output: Contribution to journalArticle

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