Ten-year follow-up of a randomized controlled trial comparing bipolar endometrial ablation with balloon ablation for heavy menstrual bleeding

M. C. Herman, J. P M Penninx, B. W. Mol, M. Y. Bongers

Research output: Contribution to journalComment/debate

Abstract

Previous randomized controlled trials compared bipolar endometrial ablation and balloon ablation for the treatment of heavy menstrual bleeding (HMB). At both 12 months and 5 years after treatment, bipolar endometrial ablation was superior to balloon ablation. This follow-up randomized controlled trial compared the effectiveness of these 2 endometrial ablation techniques in women with HMB at 10 years after treatment. The trial was conducted at a teaching hospital in the Netherlands. Subjects were 126 premenopausal women with HMB: 83 were randomized to the bipolar group and 43 to the balloon group. Women completed a follow-up questionnaire 10 years after randomization. The primary study outcome measures were amenorrhea rates, reintervention, and patient satisfaction. At the 10-year follow-up, the response rate was 83% (69/83) in the bipolar group and 81% (35/43) in the balloon group. Amenorrhea rates at 10 years were 73% (50/69) in the bipolar group and 66% (23/35) in the balloon group; the relative risk (RR) was 1.1, with a 95% confidence interval (CI) of 0.83 to 1.5. Twenty-three women required further treatment, 14 in the bipolar group and 9 in the balloon group (RR, 0.9; 95% CI, 0.63-1.3). Eight of the women required further treatment after 5 years, including 2 hysterectomies in the bipolar group. At 10 years, patient satisfaction in the bipolar group was 81% (56/69) compared with 77% (27/35) in the balloon group; the RR was 1.1, with a 95% CI of 0.82 to 1.2. These data show that that the superiority of bipolar ablation over balloon ablation in the treatment of HMB observed at 1 and 5 years after initial treatment is no longer evident after 10 years.

LanguageEnglish
Pages200-201
Number of pages2
JournalObstetrical and Gynecological Survey
Volume69
Issue number4
DOIs
Publication statusPublished - 1 Jan 2014
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

@article{a969e9bbd6cc4d94aaa94a26d0b379f2,
title = "Ten-year follow-up of a randomized controlled trial comparing bipolar endometrial ablation with balloon ablation for heavy menstrual bleeding",
abstract = "Previous randomized controlled trials compared bipolar endometrial ablation and balloon ablation for the treatment of heavy menstrual bleeding (HMB). At both 12 months and 5 years after treatment, bipolar endometrial ablation was superior to balloon ablation. This follow-up randomized controlled trial compared the effectiveness of these 2 endometrial ablation techniques in women with HMB at 10 years after treatment. The trial was conducted at a teaching hospital in the Netherlands. Subjects were 126 premenopausal women with HMB: 83 were randomized to the bipolar group and 43 to the balloon group. Women completed a follow-up questionnaire 10 years after randomization. The primary study outcome measures were amenorrhea rates, reintervention, and patient satisfaction. At the 10-year follow-up, the response rate was 83{\%} (69/83) in the bipolar group and 81{\%} (35/43) in the balloon group. Amenorrhea rates at 10 years were 73{\%} (50/69) in the bipolar group and 66{\%} (23/35) in the balloon group; the relative risk (RR) was 1.1, with a 95{\%} confidence interval (CI) of 0.83 to 1.5. Twenty-three women required further treatment, 14 in the bipolar group and 9 in the balloon group (RR, 0.9; 95{\%} CI, 0.63-1.3). Eight of the women required further treatment after 5 years, including 2 hysterectomies in the bipolar group. At 10 years, patient satisfaction in the bipolar group was 81{\%} (56/69) compared with 77{\%} (27/35) in the balloon group; the RR was 1.1, with a 95{\%} CI of 0.82 to 1.2. These data show that that the superiority of bipolar ablation over balloon ablation in the treatment of HMB observed at 1 and 5 years after initial treatment is no longer evident after 10 years.",
author = "Herman, {M. C.} and Penninx, {J. P M} and Mol, {B. W.} and Bongers, {M. Y.}",
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Ten-year follow-up of a randomized controlled trial comparing bipolar endometrial ablation with balloon ablation for heavy menstrual bleeding. / Herman, M. C.; Penninx, J. P M; Mol, B. W.; Bongers, M. Y.

In: Obstetrical and Gynecological Survey, Vol. 69, No. 4, 01.01.2014, p. 200-201.

Research output: Contribution to journalComment/debate

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T1 - Ten-year follow-up of a randomized controlled trial comparing bipolar endometrial ablation with balloon ablation for heavy menstrual bleeding

AU - Herman, M. C.

AU - Penninx, J. P M

AU - Mol, B. W.

AU - Bongers, M. Y.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Previous randomized controlled trials compared bipolar endometrial ablation and balloon ablation for the treatment of heavy menstrual bleeding (HMB). At both 12 months and 5 years after treatment, bipolar endometrial ablation was superior to balloon ablation. This follow-up randomized controlled trial compared the effectiveness of these 2 endometrial ablation techniques in women with HMB at 10 years after treatment. The trial was conducted at a teaching hospital in the Netherlands. Subjects were 126 premenopausal women with HMB: 83 were randomized to the bipolar group and 43 to the balloon group. Women completed a follow-up questionnaire 10 years after randomization. The primary study outcome measures were amenorrhea rates, reintervention, and patient satisfaction. At the 10-year follow-up, the response rate was 83% (69/83) in the bipolar group and 81% (35/43) in the balloon group. Amenorrhea rates at 10 years were 73% (50/69) in the bipolar group and 66% (23/35) in the balloon group; the relative risk (RR) was 1.1, with a 95% confidence interval (CI) of 0.83 to 1.5. Twenty-three women required further treatment, 14 in the bipolar group and 9 in the balloon group (RR, 0.9; 95% CI, 0.63-1.3). Eight of the women required further treatment after 5 years, including 2 hysterectomies in the bipolar group. At 10 years, patient satisfaction in the bipolar group was 81% (56/69) compared with 77% (27/35) in the balloon group; the RR was 1.1, with a 95% CI of 0.82 to 1.2. These data show that that the superiority of bipolar ablation over balloon ablation in the treatment of HMB observed at 1 and 5 years after initial treatment is no longer evident after 10 years.

AB - Previous randomized controlled trials compared bipolar endometrial ablation and balloon ablation for the treatment of heavy menstrual bleeding (HMB). At both 12 months and 5 years after treatment, bipolar endometrial ablation was superior to balloon ablation. This follow-up randomized controlled trial compared the effectiveness of these 2 endometrial ablation techniques in women with HMB at 10 years after treatment. The trial was conducted at a teaching hospital in the Netherlands. Subjects were 126 premenopausal women with HMB: 83 were randomized to the bipolar group and 43 to the balloon group. Women completed a follow-up questionnaire 10 years after randomization. The primary study outcome measures were amenorrhea rates, reintervention, and patient satisfaction. At the 10-year follow-up, the response rate was 83% (69/83) in the bipolar group and 81% (35/43) in the balloon group. Amenorrhea rates at 10 years were 73% (50/69) in the bipolar group and 66% (23/35) in the balloon group; the relative risk (RR) was 1.1, with a 95% confidence interval (CI) of 0.83 to 1.5. Twenty-three women required further treatment, 14 in the bipolar group and 9 in the balloon group (RR, 0.9; 95% CI, 0.63-1.3). Eight of the women required further treatment after 5 years, including 2 hysterectomies in the bipolar group. At 10 years, patient satisfaction in the bipolar group was 81% (56/69) compared with 77% (27/35) in the balloon group; the RR was 1.1, with a 95% CI of 0.82 to 1.2. These data show that that the superiority of bipolar ablation over balloon ablation in the treatment of HMB observed at 1 and 5 years after initial treatment is no longer evident after 10 years.

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M3 - Comment/debate

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