Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases

Anurag Priyam, Ben J. Woodcroft, Vivek Rai, Ismail Moghul, Alekhya Munagala, Filip Ter, Hiten Chowdhary, Iwo Pieniak, Lawrence J. Maynard, Mark Anthony Gibbins, Hong Kee Moon, Austin Davis-Richardson, Mahmut Uludag, Nathan S. Watson-Haigh, Richard Challis, Hiroyuki Nakamura, Emeline Favreau, Esteban A. Gómez, Tomás Pluskal, Guy LeonardWolfgang Rumpf, Yannick Wurm

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

Comparing newly obtained and previously known nucleotide and amino-acid sequences underpins modern biological research. BLAST is a well-established tool for such comparisons but is challenging to use on new data sets. We combined a user-centric design philosophy with sustainable software development approaches to create Sequenceserver, a tool for running BLAST and visually inspecting BLAST results for biological interpretation. Sequenceserver uses simple algorithms to prevent potential analysis errors and provides flexible text-based and visual outputs to support researcher productivity. Our software can be rapidly installed for use by individuals or on shared servers.

Original languageEnglish
Pages (from-to)2922-2924
Number of pages3
JournalMolecular Biology and Evolution
Volume36
Issue number12
DOIs
Publication statusPublished or Issued - 1 Dec 2019
Externally publishedYes

Keywords

  • BLAST
  • comparative genomics
  • sequence analysis
  • visualization

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

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