Salmonella's sensor for host defense molecules

Robert Hancock, Joseph B. McPhee

Research output: Contribution to journalShort survey

14 Citations (Scopus)

Abstract

The bacterial pathogen Salmonella typhimurium resides within phagosomes in host cells and is able to deflect the host immune response. In this issue of Cell, Bader et al. (2005) decipher an elegant mechanism by which the PhoQ sensor kinase of Salmonella is switched on by host cationic antimicrobial peptides, leading to changes in gene expression that enable Salmonella to combat the host immune response.

Original languageEnglish
Pages (from-to)320-322
Number of pages3
JournalCell
Volume122
Issue number3
DOIs
Publication statusPublished - 12 Aug 2005
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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