Risk of maternal and neonatal complications in subsequent pregnancy after planned caesarean section in a first birth, compared with emergency caesarean section: A nationwide comparative cohort study

N. Kok, L. Ruiter, M. Hof, A. Ravelli, B. W. Mol, E. Pajkrt, B. Kazemier

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objective To compare the difference in risks of neonatal and maternal complications, including uterine rupture, in a second birth following a planned caesarean section versus emergency caesarean section in the first birth. Design Prospective cohort study. Setting Population-based cohort in the Netherlands. Population Linked data set of outcomes for term caesarean section in a first birth followed by a consecutive delivery. Methods We conducted a prospective cohort analysis using data from the Dutch Perinatal Registry. We included primiparous women who gave birth to term singleton infants through planned or emergency caesarean from January 2000 through December 2007, and who had a second singleton delivery during the same period (n = 41 109). Odds ratios and adjusted odds ratios were calculated. Main outcome measures Maternal and neonatal complications, specifically uterine rupture, in second births associated with planned and emergency caesareans in the first birth. Results Women with a history of a planned caesarean section in the first birth (n = 11 445) had a 0.24% risk for uterine rupture, compared with a 0.16% risk for women with a history of emergency caesarean section (n = 29 664; aOR 1.4, 95% CI 0.8-2.4). In multivariate logistic regression, women with planned caesareans in a first birth had a significantly increased risk of stillbirth (aOR 1.5, 95% CI 1.0-2.2) and postpartum haemorrhage (aOR 1.1, 95% CI 1.0-1.2) in second births, compared with women with emergency caesareans in the first birth. Conclusions We found a moderately increased risk of postpartum haemorrhage and a small to moderately increased risk of uterine rupture and stillbirth as a long-term effect of prior planned caesarean delivery on second births.

LanguageEnglish
Pages216-223
Number of pages8
JournalBJOG: An International Journal of Obstetrics and Gynaecology
Volume121
Issue number2
DOIs
Publication statusPublished - Jan 2014

Keywords

  • Emergency caesarean section
  • planned caesarean section
  • postpartum haemorrhage
  • stillbirth
  • uterine rupture
  • vaginal birth after caesarean

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

@article{2450cc7fc73f4d739285cca697c0a2fd,
title = "Risk of maternal and neonatal complications in subsequent pregnancy after planned caesarean section in a first birth, compared with emergency caesarean section: A nationwide comparative cohort study",
abstract = "Objective To compare the difference in risks of neonatal and maternal complications, including uterine rupture, in a second birth following a planned caesarean section versus emergency caesarean section in the first birth. Design Prospective cohort study. Setting Population-based cohort in the Netherlands. Population Linked data set of outcomes for term caesarean section in a first birth followed by a consecutive delivery. Methods We conducted a prospective cohort analysis using data from the Dutch Perinatal Registry. We included primiparous women who gave birth to term singleton infants through planned or emergency caesarean from January 2000 through December 2007, and who had a second singleton delivery during the same period (n = 41 109). Odds ratios and adjusted odds ratios were calculated. Main outcome measures Maternal and neonatal complications, specifically uterine rupture, in second births associated with planned and emergency caesareans in the first birth. Results Women with a history of a planned caesarean section in the first birth (n = 11 445) had a 0.24{\%} risk for uterine rupture, compared with a 0.16{\%} risk for women with a history of emergency caesarean section (n = 29 664; aOR 1.4, 95{\%} CI 0.8-2.4). In multivariate logistic regression, women with planned caesareans in a first birth had a significantly increased risk of stillbirth (aOR 1.5, 95{\%} CI 1.0-2.2) and postpartum haemorrhage (aOR 1.1, 95{\%} CI 1.0-1.2) in second births, compared with women with emergency caesareans in the first birth. Conclusions We found a moderately increased risk of postpartum haemorrhage and a small to moderately increased risk of uterine rupture and stillbirth as a long-term effect of prior planned caesarean delivery on second births.",
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author = "N. Kok and L. Ruiter and M. Hof and A. Ravelli and Mol, {B. W.} and E. Pajkrt and B. Kazemier",
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Risk of maternal and neonatal complications in subsequent pregnancy after planned caesarean section in a first birth, compared with emergency caesarean section : A nationwide comparative cohort study. / Kok, N.; Ruiter, L.; Hof, M.; Ravelli, A.; Mol, B. W.; Pajkrt, E.; Kazemier, B.

In: BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 121, No. 2, 01.2014, p. 216-223.

Research output: Contribution to journalArticle

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T1 - Risk of maternal and neonatal complications in subsequent pregnancy after planned caesarean section in a first birth, compared with emergency caesarean section

T2 - BJOG: An International Journal of Obstetrics and Gynaecology

AU - Kok, N.

AU - Ruiter, L.

AU - Hof, M.

AU - Ravelli, A.

AU - Mol, B. W.

AU - Pajkrt, E.

AU - Kazemier, B.

PY - 2014/1

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N2 - Objective To compare the difference in risks of neonatal and maternal complications, including uterine rupture, in a second birth following a planned caesarean section versus emergency caesarean section in the first birth. Design Prospective cohort study. Setting Population-based cohort in the Netherlands. Population Linked data set of outcomes for term caesarean section in a first birth followed by a consecutive delivery. Methods We conducted a prospective cohort analysis using data from the Dutch Perinatal Registry. We included primiparous women who gave birth to term singleton infants through planned or emergency caesarean from January 2000 through December 2007, and who had a second singleton delivery during the same period (n = 41 109). Odds ratios and adjusted odds ratios were calculated. Main outcome measures Maternal and neonatal complications, specifically uterine rupture, in second births associated with planned and emergency caesareans in the first birth. Results Women with a history of a planned caesarean section in the first birth (n = 11 445) had a 0.24% risk for uterine rupture, compared with a 0.16% risk for women with a history of emergency caesarean section (n = 29 664; aOR 1.4, 95% CI 0.8-2.4). In multivariate logistic regression, women with planned caesareans in a first birth had a significantly increased risk of stillbirth (aOR 1.5, 95% CI 1.0-2.2) and postpartum haemorrhage (aOR 1.1, 95% CI 1.0-1.2) in second births, compared with women with emergency caesareans in the first birth. Conclusions We found a moderately increased risk of postpartum haemorrhage and a small to moderately increased risk of uterine rupture and stillbirth as a long-term effect of prior planned caesarean delivery on second births.

AB - Objective To compare the difference in risks of neonatal and maternal complications, including uterine rupture, in a second birth following a planned caesarean section versus emergency caesarean section in the first birth. Design Prospective cohort study. Setting Population-based cohort in the Netherlands. Population Linked data set of outcomes for term caesarean section in a first birth followed by a consecutive delivery. Methods We conducted a prospective cohort analysis using data from the Dutch Perinatal Registry. We included primiparous women who gave birth to term singleton infants through planned or emergency caesarean from January 2000 through December 2007, and who had a second singleton delivery during the same period (n = 41 109). Odds ratios and adjusted odds ratios were calculated. Main outcome measures Maternal and neonatal complications, specifically uterine rupture, in second births associated with planned and emergency caesareans in the first birth. Results Women with a history of a planned caesarean section in the first birth (n = 11 445) had a 0.24% risk for uterine rupture, compared with a 0.16% risk for women with a history of emergency caesarean section (n = 29 664; aOR 1.4, 95% CI 0.8-2.4). In multivariate logistic regression, women with planned caesareans in a first birth had a significantly increased risk of stillbirth (aOR 1.5, 95% CI 1.0-2.2) and postpartum haemorrhage (aOR 1.1, 95% CI 1.0-1.2) in second births, compared with women with emergency caesareans in the first birth. Conclusions We found a moderately increased risk of postpartum haemorrhage and a small to moderately increased risk of uterine rupture and stillbirth as a long-term effect of prior planned caesarean delivery on second births.

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KW - vaginal birth after caesarean

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