Risk factors for total knee arthroplasty aseptic revision

Robert S Namba, Guy Cafri, Monti Khatod, Maria C S Inacio, Timothy W Brox, Elizabeth W Paxton

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Using a Total Joint Replacement Registry, patient, operative, implant, surgeon, and hospital risk factors associated with aseptic revision after primary total knee arthroplasty (TKA) were evaluated. From 04/2001 to 12/31/2010 64,017 primary TKA cases, followed for a median time of 2.9 years, were registered and included in the analysis. Patients were predominantly female, white, with osteoarthritis, and obese. The crude aseptic revision rate is 1.3% (N=826). The cumulative survival for aseptic revision at 8 years is 97.6% (95% CI 97.3%-97.8%). Adjusted models revealed that age, race, body mass index, diabetic status, bilateral procedures, high-flex implants, and the LCS mobile bearing knee are associated with risk of revision. Gender, general health status, diagnosis, surgeon fellowship training, surgeon volume, hospital volume, fixation, and bearing surface material were not associated with risk of aseptic revision. Recognition of surgical factors associated with TKA failures can help the surgeons with their choices of surgical techniques and implants.

Original languageEnglish
Pages (from-to)122-7
Number of pages6
JournalJournal of Arthroplasty
Issue number8 Suppl
Publication statusPublished or Issued - Sep 2013


  • Age Factors
  • Aged
  • Arthroplasty, Replacement, Knee
  • Body Mass Index
  • Continental Population Groups
  • Female
  • Humans
  • Knee Joint
  • Knee Prosthesis
  • Male
  • Middle Aged
  • Prospective Studies
  • Prosthesis Failure
  • Reoperation
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Journal Article

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