Reconstruction of the anterior cruciate ligament: association of graft choice with increased risk of early revision

G B Maletis, M C S Inacio, J L Desmond, T T Funahashi

Research output: Contribution to journalArticle

89 Citations (Scopus)


We examined the association of graft type with the risk of early revision of primary anterior cruciate ligament reconstruction (ACLR) in a community-based sample. A retrospective analysis of a cohort of 9817 ACLRs recorded in an ACLR Registry was performed. Patients were included if they underwent primary ACLR with bone-patellar tendon-bone autograft, hamstring tendon autograft or allograft tissue. Aseptic failure was the main endpoint of the study. After adjusting for age, gender, ethnicity, and body mass index, allografts had a 3.02 times (95% confidence interval (CI) 1.93 to 4.72) higher risk of aseptic revision than bone-patellar tendon-bone autografts (p < 0.001). Hamstring tendon autografts had a 1.82 times (95% CI 1.10 to 3.00) higher risk of revision compared with bone-patellar tendon-bone autografts (p = 0.019). For each year increase in age, the risk of revision decreased by 7% (95% CI 5 to 9). In gender-specific analyses a 2.26 times (95% CI 1.15 to 4.44) increased risk of hamstring tendon autograft revision in females was observed compared with bone-patellar tendon-bone autograft. We conclude that allograft tissue, hamstring tendon autografts, and younger age may all increase the risk of early revision surgery after ACLR.

Number of pages6
JournalBone and Joint Journal
Issue number5
Publication statusPublished - May 2013


  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anterior Cruciate Ligament
  • Anterior Cruciate Ligament Injuries
  • Anterior Cruciate Ligament Reconstruction
  • Bone-Patellar Tendon-Bone Grafting
  • Child
  • Female
  • Humans
  • Male
  • Middle Aged
  • Registries
  • Reoperation
  • Retrospective Studies
  • Tendons
  • Transplantation, Autologous
  • Transplantation, Homologous
  • Young Adult
  • Journal Article

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