TY - JOUR
T1 - Recent trends in coronary intravascular ultrasound
T2 - Tracking atherosclerosis, pursuit of vulnerable plaques, and beyond
AU - Sipahi, Ilke
AU - Nicholls, Stephen J.
AU - Tuzcu, E. Murat
N1 - Funding Information:
Dr Sipahi has received an educational grant, Dr Nicholls has received lecture honoraria, and Dr Tuzcu has received research support and lecture honoraria from Pfizer.
PY - 2006/1
Y1 - 2006/1
N2 - Within the past decade, intravascular ultrasound (IVUS) has proved to be a useful modality for guiding coronary interventions and assessment of cardiac allograft vasculopathy. During the last few years, IVUS has been used increasingly for the evaluation of the efficacy of various possible antiatherosclerotic therapies including high-dose statins, antihypertensives, and recombinant apolipoprotein A-I Milano. The recently introduced radiofrequency signal analysis is an advanced method for evaluation of IVUS signals to determine various histologic components of atherosclerotic plaques. Elastography is an allied technology for measuring the tissue strain that occurs in response to changes in intraluminal pressure. Whether radiofrequency signal analysis or elastography will become clinically useful tools for detecting vulnerable plaques remains an unanswered, burning question.
AB - Within the past decade, intravascular ultrasound (IVUS) has proved to be a useful modality for guiding coronary interventions and assessment of cardiac allograft vasculopathy. During the last few years, IVUS has been used increasingly for the evaluation of the efficacy of various possible antiatherosclerotic therapies including high-dose statins, antihypertensives, and recombinant apolipoprotein A-I Milano. The recently introduced radiofrequency signal analysis is an advanced method for evaluation of IVUS signals to determine various histologic components of atherosclerotic plaques. Elastography is an allied technology for measuring the tissue strain that occurs in response to changes in intraluminal pressure. Whether radiofrequency signal analysis or elastography will become clinically useful tools for detecting vulnerable plaques remains an unanswered, burning question.
UR - http://www.scopus.com/inward/record.url?scp=32044433347&partnerID=8YFLogxK
U2 - 10.1016/j.nuclcard.2005.11.001
DO - 10.1016/j.nuclcard.2005.11.001
M3 - Article
C2 - 16464722
AN - SCOPUS:32044433347
VL - 13
SP - 91
EP - 96
JO - Journal of Nuclear Cardiology
JF - Journal of Nuclear Cardiology
SN - 1071-3581
IS - 1
ER -