Rationale, design, and demographic characteristics of the handan offspring myopia study

Tie Ying Gao, Peng Zhang, Lei Li, Zhong Lin, Vishal Jhanji, Andrea Peng, Zhen Wu Li, Lan Ping Sun, Wei Han, Ning Li Wang, Yuan Bo Liang

Research output: Contribution to journalArticle

7 Citations (Scopus)


Purpose: The Handan Offspring Myopia Study (HOMS) aims to investigate the familial associations of myopia between parents and their offspring. Methods: Children aged 6-18 years, residing in 6 villages where all people aged 30 years had participated in The Handan Eye Study in 2006-2007, were selected for the current eye study between March and June 2010. A mobile clinic was set up in the 6 villages for comprehensive eye examinations, including visual acuity, ocular biometry, cycloplegic autorefraction and retinal photography. Results: Of 1238 eligible individuals, 878 children (70.2%; 52.6% male) from 541 families were recruited. Mean age of the children was 10.5±2.5 years. The prevalence of myopia (spherical equivalent refraction <-0.5 diopter) was 23.5% (males 16.8%, females 30.8%). The prevalence of low vision (presenting visual acuity 20/400 but <20/60) in the better eye was 7.1%. A higher number of females had low vision at the time of presentation (9.2%) compared to males (5.2%, p=0.02). The prevalence of low vision in the worse eye was 10.6% (males 6.7%, females 14.9%, p<0.001). The majority of visual impairment in the better-seeing (56/62, 90.3%) as well as the worse-seeing (84/93, 90.3%) eye was correctable. Conclusions: The HOMS examined about 70% of eligible Han Chinese offspring of Handan Eye Study participants in a rural region of northern China. Results from the HOMS will provide key information about the prevalence of refractive errors and eye diseases in rural Chinese children.

Original languageEnglish
Pages (from-to)124-132
Number of pages9
JournalOphthalmic Epidemiology
Issue number2
Publication statusPublished - 1 Jan 2014


  • Children
  • Epidemiology
  • Low vision
  • Myopia
  • Offspring
  • Prevalence

ASJC Scopus subject areas

  • Epidemiology
  • Ophthalmology

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