Prostaglandins and Leukotrienes

Gillian Caughey, M. J. James, L. G. Cleland

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Prostaglandins (PGs) and leukotrienes are lipid mediators belonging to the eicosanoid family. They are synthesized from arachidonic acid, a polyunsaturated fatty acid, via a tightly regulated pathway. A key enzyme in the synthetic pathway, cyclooxygenase, has been the target for the pharmacological modulation of PG-mediated clinical manifestations. Eicosanoids generally act as paracrine or autocrine agents and are involved in the maintenance of homeostatic processes as well as in the pathophysiology of several chronic diseases.

LanguageEnglish
Title of host publicationEncyclopedia of Human Nutrition (Third edition)
PublisherElsevier Inc.
Pages104-110
Number of pages7
Volume4-4
ISBN (Electronic)9780123848857
ISBN (Print)9780123750839
DOIs
Publication statusPublished - 1 Jan 2012
Externally publishedYes

Keywords

  • Arachidonic acid
  • Cyclooxygenase
  • Eicosanoids
  • Leukotrienes
  • Lipoxygenase
  • Prostaglandin

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Caughey, G., James, M. J., & Cleland, L. G. (2012). Prostaglandins and Leukotrienes. In Encyclopedia of Human Nutrition (Third edition) (Vol. 4-4, pp. 104-110). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-375083-9.00238-5
Caughey, Gillian ; James, M. J. ; Cleland, L. G. / Prostaglandins and Leukotrienes. Encyclopedia of Human Nutrition (Third edition). Vol. 4-4 Elsevier Inc., 2012. pp. 104-110
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Caughey, G, James, MJ & Cleland, LG 2012, Prostaglandins and Leukotrienes. in Encyclopedia of Human Nutrition (Third edition). vol. 4-4, Elsevier Inc., pp. 104-110. https://doi.org/10.1016/B978-0-12-375083-9.00238-5

Prostaglandins and Leukotrienes. / Caughey, Gillian; James, M. J.; Cleland, L. G.

Encyclopedia of Human Nutrition (Third edition). Vol. 4-4 Elsevier Inc., 2012. p. 104-110.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Caughey G, James MJ, Cleland LG. Prostaglandins and Leukotrienes. In Encyclopedia of Human Nutrition (Third edition). Vol. 4-4. Elsevier Inc. 2012. p. 104-110 https://doi.org/10.1016/B978-0-12-375083-9.00238-5