Prevalence of exfoliation syndrome in central Sri Lanka: The Kandy eye study

A. K. Rudkin, K. Edussuriya, S. Sennanayake, T. Senaratne, D. Selva, Thomas Sullivan, R. J. Casson

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Aims: To report the prevalence and correlates of exfoliation syndrome (XFS) in central, rural Sri Lanka. Methods: A population-based, cross-sectional ophthalmic survey of inhabitants 40 years of age and over from villages in the Kandy District was conducted. Selection was randomised using a cluster sampling process. 1721 eligible participants were identified, 1375 participated. A detailed ophthalmic history and examination including ocular biometry was made of each participant. Results: The prevalence of XFS was estimated to be 1.1% (95% Cl 0.5 to 1.5%; 22 eyes). XFS was bilateral in eight subjects, unilateral in six subjects. Univariate analysis demonstrated a significant association between XFS and increasing age (p<0.001), increasing intraocular pressure (odds ratio 1.2; 95% Cl 1.09 to 1.27; p<0.001), nuclear cataracts (odds ratio 1.92; 95% Cl 1.47 to 2.51; p<0.001), visual impairment (odds ratio 9.72; 95% Cl 3.01 to 31.44; p<0.001) and a history of hypertension (odds ratio 3.89; 95% Cl 1.14 to 13.16; p = 0.030). Conclusion: XFS in this Sri Lankan population was associated with advanced age, raised intraocular pressure, nuclear cataracts, hypertension and visual impairment.

Original languageEnglish
Pages (from-to)1595-1598
Number of pages4
JournalBritish Journal of Ophthalmology
Issue number12
Publication statusPublished - 1 Dec 2008
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Rudkin, A. K., Edussuriya, K., Sennanayake, S., Senaratne, T., Selva, D., Sullivan, T., & Casson, R. J. (2008). Prevalence of exfoliation syndrome in central Sri Lanka: The Kandy eye study. British Journal of Ophthalmology, 92(12), 1595-1598.