Optimization of whispering gallery resonator design for biosensing applications

T. Reynolds, M. R. Henderson, A. François, N. Riesen, J. M M Hall, S. V. Afshar, S. J. Nicholls, T. M. Monro

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21 Citations (Scopus)

Abstract

Whispering gallery modes (WGMs) within microsphere cavities enable highly sensitive label-free detection of changes in the surrounding refractive index. This detection modality is of particular interest for biosensing applications. However, the majority of biosensing work utilizing WGMs to date has been conducted with resonators made from either silica or polystyrene, while other materials remain largely uninvestigated. By considering characteristics such as the quality factor and sensitivity of the resonator, the optimal WGM sensor design can be identified for various applications. This work explores the choice of resonator refractive index and size to provide design guidelines for undertaking refractive index biosensing using WGMs.

LanguageEnglish
Pages17067-17076
Number of pages10
JournalOptics Express
Volume23
Issue number13
DOIs
Publication statusPublished - 29 Jun 2015

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Reynolds, T., Henderson, M. R., François, A., Riesen, N., Hall, J. M. M., Afshar, S. V., ... Monro, T. M. (2015). Optimization of whispering gallery resonator design for biosensing applications. Optics Express, 23(13), 17067-17076. https://doi.org/10.1364/OE.23.017067