Muscle strength gains during resistance exercise training are attenuated with soy compared with dairy or usual protein intake in older adults: A randomized controlled trial

Rebecca L. Thomson, Grant D. Brinkworth, Manny Noakes, Jonathan D. Buckley

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background and aims: Maintenance of muscle mass and strength into older age is critical to maintain health. The aim was to determine whether increased dairy or soy protein intake combined with resistance training enhanced strength gains in older adults. Methods: 179 healthy older adults (age 61.5 ± 7.4 yrs, BMI 27.6 ± 3.6 kg/m2) performed resistance training three times per week for 12 weeks and were randomized to one of three eucaloric dietary treatments which delivered >20 g of protein at each main meal or immediately after resistance training: high dairy protein (HP-D, >1.2 g of protein/kg body weight/d; ~27 g/d dairy protein); high soy protein (HP-S, >1.2 g of protein/kg body weight/d; ~27 g/d soy protein); usual protein intake (UP, <1.2 g of protein/kg body weight/d). Muscle strength, body composition, physical function and quality of life were assessed at baseline and 12 weeks. Treatments effects were analyzed using two-way ANOVA. Results: 83 participants completed the intervention per protocol (HP-D = 34, HP-S = 26, UP = 23). Protein intake was higher in HP-D and HP-S compared with UP (HP-D 1.41 ± 0.14 g/kg/d, HP-S 1.42 ± 0.61 g/kg/d, UP 1.10 ± 0.10 g/kg/d; P < 0.001 treatment effect). Strength increased less in HP-S compared with HP-D and UP (HP-D 92.1 ± 40.8%, HP-S 63.0 ± 23.8%,UP 92.3 ± 35.4%; P = 0.002 treatment effect). Lean mass, physical function and mental health scores increased and fat mass decreased (P ≤ 0.006), with no treatment effect (P > 0.06). Conclusions: Increased soy protein intake attenuated gains in muscle strength during resistance training in older adults compared with increased intake of dairy protein or usual protein intake.Clinical Trial Registration: ACTRN12612000177853 www.anzctr.org.au.

LanguageEnglish
Pages27-33
Number of pages7
JournalClinical Nutrition
Volume35
Issue number1
DOIs
Publication statusPublished - 1 Feb 2016

Keywords

  • Dairy
  • Older adults
  • Protein
  • Resistance training
  • Soy
  • Strength

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Critical Care and Intensive Care Medicine

Cite this

@article{09da942c7bf946dcb48ce21b4a3bef2a,
title = "Muscle strength gains during resistance exercise training are attenuated with soy compared with dairy or usual protein intake in older adults: A randomized controlled trial",
abstract = "Background and aims: Maintenance of muscle mass and strength into older age is critical to maintain health. The aim was to determine whether increased dairy or soy protein intake combined with resistance training enhanced strength gains in older adults. Methods: 179 healthy older adults (age 61.5 ± 7.4 yrs, BMI 27.6 ± 3.6 kg/m2) performed resistance training three times per week for 12 weeks and were randomized to one of three eucaloric dietary treatments which delivered >20 g of protein at each main meal or immediately after resistance training: high dairy protein (HP-D, >1.2 g of protein/kg body weight/d; ~27 g/d dairy protein); high soy protein (HP-S, >1.2 g of protein/kg body weight/d; ~27 g/d soy protein); usual protein intake (UP, <1.2 g of protein/kg body weight/d). Muscle strength, body composition, physical function and quality of life were assessed at baseline and 12 weeks. Treatments effects were analyzed using two-way ANOVA. Results: 83 participants completed the intervention per protocol (HP-D = 34, HP-S = 26, UP = 23). Protein intake was higher in HP-D and HP-S compared with UP (HP-D 1.41 ± 0.14 g/kg/d, HP-S 1.42 ± 0.61 g/kg/d, UP 1.10 ± 0.10 g/kg/d; P < 0.001 treatment effect). Strength increased less in HP-S compared with HP-D and UP (HP-D 92.1 ± 40.8{\%}, HP-S 63.0 ± 23.8{\%},UP 92.3 ± 35.4{\%}; P = 0.002 treatment effect). Lean mass, physical function and mental health scores increased and fat mass decreased (P ≤ 0.006), with no treatment effect (P > 0.06). Conclusions: Increased soy protein intake attenuated gains in muscle strength during resistance training in older adults compared with increased intake of dairy protein or usual protein intake.Clinical Trial Registration: ACTRN12612000177853 www.anzctr.org.au.",
keywords = "Dairy, Older adults, Protein, Resistance training, Soy, Strength",
author = "Thomson, {Rebecca L.} and Brinkworth, {Grant D.} and Manny Noakes and Buckley, {Jonathan D.}",
year = "2016",
month = "2",
day = "1",
doi = "10.1016/j.clnu.2015.01.018",
language = "English",
volume = "35",
pages = "27--33",
journal = "Clinical Nutrition",
issn = "0261-5614",
publisher = "Churchill Livingstone",
number = "1",

}

Muscle strength gains during resistance exercise training are attenuated with soy compared with dairy or usual protein intake in older adults : A randomized controlled trial. / Thomson, Rebecca L.; Brinkworth, Grant D.; Noakes, Manny; Buckley, Jonathan D.

In: Clinical Nutrition, Vol. 35, No. 1, 01.02.2016, p. 27-33.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Muscle strength gains during resistance exercise training are attenuated with soy compared with dairy or usual protein intake in older adults

T2 - Clinical Nutrition

AU - Thomson, Rebecca L.

AU - Brinkworth, Grant D.

AU - Noakes, Manny

AU - Buckley, Jonathan D.

PY - 2016/2/1

Y1 - 2016/2/1

N2 - Background and aims: Maintenance of muscle mass and strength into older age is critical to maintain health. The aim was to determine whether increased dairy or soy protein intake combined with resistance training enhanced strength gains in older adults. Methods: 179 healthy older adults (age 61.5 ± 7.4 yrs, BMI 27.6 ± 3.6 kg/m2) performed resistance training three times per week for 12 weeks and were randomized to one of three eucaloric dietary treatments which delivered >20 g of protein at each main meal or immediately after resistance training: high dairy protein (HP-D, >1.2 g of protein/kg body weight/d; ~27 g/d dairy protein); high soy protein (HP-S, >1.2 g of protein/kg body weight/d; ~27 g/d soy protein); usual protein intake (UP, <1.2 g of protein/kg body weight/d). Muscle strength, body composition, physical function and quality of life were assessed at baseline and 12 weeks. Treatments effects were analyzed using two-way ANOVA. Results: 83 participants completed the intervention per protocol (HP-D = 34, HP-S = 26, UP = 23). Protein intake was higher in HP-D and HP-S compared with UP (HP-D 1.41 ± 0.14 g/kg/d, HP-S 1.42 ± 0.61 g/kg/d, UP 1.10 ± 0.10 g/kg/d; P < 0.001 treatment effect). Strength increased less in HP-S compared with HP-D and UP (HP-D 92.1 ± 40.8%, HP-S 63.0 ± 23.8%,UP 92.3 ± 35.4%; P = 0.002 treatment effect). Lean mass, physical function and mental health scores increased and fat mass decreased (P ≤ 0.006), with no treatment effect (P > 0.06). Conclusions: Increased soy protein intake attenuated gains in muscle strength during resistance training in older adults compared with increased intake of dairy protein or usual protein intake.Clinical Trial Registration: ACTRN12612000177853 www.anzctr.org.au.

AB - Background and aims: Maintenance of muscle mass and strength into older age is critical to maintain health. The aim was to determine whether increased dairy or soy protein intake combined with resistance training enhanced strength gains in older adults. Methods: 179 healthy older adults (age 61.5 ± 7.4 yrs, BMI 27.6 ± 3.6 kg/m2) performed resistance training three times per week for 12 weeks and were randomized to one of three eucaloric dietary treatments which delivered >20 g of protein at each main meal or immediately after resistance training: high dairy protein (HP-D, >1.2 g of protein/kg body weight/d; ~27 g/d dairy protein); high soy protein (HP-S, >1.2 g of protein/kg body weight/d; ~27 g/d soy protein); usual protein intake (UP, <1.2 g of protein/kg body weight/d). Muscle strength, body composition, physical function and quality of life were assessed at baseline and 12 weeks. Treatments effects were analyzed using two-way ANOVA. Results: 83 participants completed the intervention per protocol (HP-D = 34, HP-S = 26, UP = 23). Protein intake was higher in HP-D and HP-S compared with UP (HP-D 1.41 ± 0.14 g/kg/d, HP-S 1.42 ± 0.61 g/kg/d, UP 1.10 ± 0.10 g/kg/d; P < 0.001 treatment effect). Strength increased less in HP-S compared with HP-D and UP (HP-D 92.1 ± 40.8%, HP-S 63.0 ± 23.8%,UP 92.3 ± 35.4%; P = 0.002 treatment effect). Lean mass, physical function and mental health scores increased and fat mass decreased (P ≤ 0.006), with no treatment effect (P > 0.06). Conclusions: Increased soy protein intake attenuated gains in muscle strength during resistance training in older adults compared with increased intake of dairy protein or usual protein intake.Clinical Trial Registration: ACTRN12612000177853 www.anzctr.org.au.

KW - Dairy

KW - Older adults

KW - Protein

KW - Resistance training

KW - Soy

KW - Strength

UR - http://www.scopus.com/inward/record.url?scp=84925252764&partnerID=8YFLogxK

U2 - 10.1016/j.clnu.2015.01.018

DO - 10.1016/j.clnu.2015.01.018

M3 - Article

VL - 35

SP - 27

EP - 33

JO - Clinical Nutrition

JF - Clinical Nutrition

SN - 0261-5614

IS - 1

ER -