Monitoring disease response in chronic-phase chronic myeloid leukemia: the age of molecular assays?

David T. Yeung, Susan Branford

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)


An 80-year-old man has newly diagnosed chronic myeloid leukemia. His BM and blood examination at diagnosis confirms chronic-phase disease, with the Philadelphia chromosome as the sole cytogenetic abnormality. He has intermediate Sokal and Hasford risk,(1) and is started on imatinib 600 mg once daily. He lives 5 hours away from the nearest specialist hematology service and prefers followup with his local physician, who cannot perform BM examinations. In patients such as this, is it acceptable to monitor his therapeutic response solely with molecular studies of his peripheral blood?

Original languageEnglish
Pages (from-to)111-114
Number of pages4
JournalHematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program
Publication statusPublished or Issued - 2012
Externally publishedYes

ASJC Scopus subject areas

  • Hematology

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