Molecular bases of pathological growth

J. Argente, Luis Perez-Jurado, J. F. Sotos

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)

Abstract

Due to the tremendous advances in molecular biology techniques in recent years, our knowledge of the genetic basis of pathological human growth has expanded dramatically. Pathological growth includes both overgrowth and under-growth, with undergrowth being generally classified into either proportionate or disproportionate growth. Each of these classifications of pathological human growth can now be associated with specific gene alterations. Here we review the different genes, and their various alterations, that are currently known to be implicated in these processes.

Original languageEnglish
Pages (from-to)179-210
Number of pages32
JournalJournal of Endocrine Genetics
Volume1
Issue number4
Publication statusPublished or Issued - 1 Jan 2000
Externally publishedYes

Keywords

  • Genes
  • Overgrowth
  • Short stature
  • Skeletal dysplasias

ASJC Scopus subject areas

  • Genetics
  • Endocrinology
  • Genetics(clinical)

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