Method Of Purifying RNA Binding Protein-RNA Complexes

Kirk Jensen (Inventor)

Research output: Patent

Abstract

The present invention provides methods for purifying RNA molecules interacting with an RNA binding protein (RBP), and the use of such methods to analyze a gene expression profile of a cell. The invention also provides sequences of RNA molecules that mediate binding to an RBP, proteins encoded by the sequences, a method of identifying the sequences, and the use of the sequences in a screen to identify bioactive molecules. The invention also provides RNA motifs found among the sequences and compounds that bind the RNA motifs. In addition, the invention provides methods of treating diseases associated with a function of an RNA binding protein.
LanguageEnglish
Patent numberUS 9447454 B2
IPCUS 9447454 B2
Publication statusPublished - 20 Sep 2016

Cite this

Jensen, K. (2016). IPC No. US 9447454 B2. Method Of Purifying RNA Binding Protein-RNA Complexes. (Patent No. US 9447454 B2). United States Patent & Trademark Office.