Measuring brain stimulation induced changes in cortical properties using TMS-EEG

Sung Wook Chung, Nigel Rogasch, Kate E. Hoy, Paul B. Fitzgerald

Research output: Contribution to journalReview article

47 Citations (Scopus)

Abstract

Neuromodulatory brain stimulation can induce plastic reorganization of cortical circuits that persist beyond the period of stimulation. Most of our current knowledge about the physiological properties has been derived from the motor cortex. The integration of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) is a valuable method for directly probing excitability, connectivity and oscillatory dynamics of regions throughout the brain. Offering in depth measurement of cortical reactivity, TMS-EEG allows the evaluation of TMS-evoked components that may act as a marker for cortical excitation and inhibition. A growing body of research is using concurrent TMS and EEG (TMS-EEG) to explore the effects of different neuromodulatory techniques such as repetitive TMS and transcranial direct current stimulation on cortical function, particularly in non-motor regions. In this review, we outline studies examining TMS-evoked potentials and oscillations before and after, or during a single session of brain stimulation. Investigating these studies will aid in our understanding of mechanisms involved in the modulation of excitability and inhibition by neuroplasticity following different stimulation paradigms.

LanguageEnglish
Pages1010-1020
Number of pages11
JournalBrain Stimulation
Volume8
Issue number6
DOIs
Publication statusPublished - 1 Nov 2015
Externally publishedYes

Keywords

  • Cortical excitability
  • Electroencephalography (EEG)
  • Neuromodulation
  • TMS-Evoked potential (TEP)
  • Transcranial magnetic stimulation (TMS)

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biophysics
  • Clinical Neurology

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