Magnetic resonance assessment of prevalence and correlates of right ventricular abnormalities in isolated left ventricular noncompaction

Gaetano Nucifora, Giovanni D. Aquaro, Pier Giorgio Masci, Alessandro Pingitore, Massimo Lombardi

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The aim of the present study was to evaluate the prevalence and correlates of right ventricular (RV) noncompaction (RVNC), RV systolic dysfunction, and RV myocardial fibrosis in patients with isolated left ventricular (LV) noncompaction (LVNC). For this purpose, cine and contrast-enhanced cardiac magnetic resonance imaging (MRI) was used. A total of 56 consecutive patients with isolated LVNC were included in the study. The diagnosis of isolated LVNC was based on the presence of standard cardiac MRI and clinical criteria. For each patient, cine and contrast-enhanced cardiac MR images were analyzed to evaluate the prevalence and correlates of RVNC, RV dysfunction, and late gadolinium enhancement (a surrogate of myocardial fibrosis) involving the RV. Mean age of the patient population was 45 ± 19 years; 35 patients (63%) were men. RVNC was observed in 5 patients (9%). Impaired RV systolic function was observed in 9 patients (16%). Late gadolinium enhancement was not observed in any RV segment. No association was found between wall motion abnormalities and noncompaction at RV segmental level (φ coefficient 0.041, p = 0.26). At multivariate analysis, LV ejection fraction was the only variable independently related to RV ejection fraction (β = 0.62, p <0.001). In conclusion, RV systolic dysfunction is present in a non-negligible proportion of patients with isolated LVNC; LV systolic function is the only variable independently related to RV systolic function.

LanguageEnglish
Pages142-146
Number of pages5
JournalAmerican Journal of Cardiology
Volume113
Issue number1
DOIs
Publication statusPublished - 1 Jan 2014

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Nucifora, Gaetano ; Aquaro, Giovanni D. ; Masci, Pier Giorgio ; Pingitore, Alessandro ; Lombardi, Massimo. / Magnetic resonance assessment of prevalence and correlates of right ventricular abnormalities in isolated left ventricular noncompaction. In: American Journal of Cardiology. 2014 ; Vol. 113, No. 1. pp. 142-146.
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Magnetic resonance assessment of prevalence and correlates of right ventricular abnormalities in isolated left ventricular noncompaction. / Nucifora, Gaetano; Aquaro, Giovanni D.; Masci, Pier Giorgio; Pingitore, Alessandro; Lombardi, Massimo.

In: American Journal of Cardiology, Vol. 113, No. 1, 01.01.2014, p. 142-146.

Research output: Contribution to journalArticle

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