Li-gazing at the crest: Modulation of the neural crest by the ubiquitin pathway

Sophie Wiszniak, Rachael Lumb, Samuela Kabbara, Michaela Scherer, Quenten Schwarz

Research output: Contribution to journalShort survey

3 Citations (Scopus)

Abstract

Neural crest cells are a transient population of stem cells that give rise to a diverse range of cell types during embryonic development. Through gain-of-function and loss-of-function studies in several model organisms many key signalling pathways and cell-type specific transcription factors essential for neural crest cell development have been identified. However, the role of post-translational regulation remains largely unexplored. Here we review this cell type with a foray into the known and potential roles of the ubiquitination pathway in key signalling events during neural crest cell development.

Original languageEnglish
Pages (from-to)1087-1091
Number of pages5
JournalInternational Journal of Biochemistry and Cell Biology
Volume45
Issue number6
DOIs
Publication statusPublished - 1 Jan 2013

Keywords

  • Neural crest
  • Stem cell
  • Ubiquitin

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology

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