Intervention with PTCA and CABG following thrombolysis for acute myocardial infarction: Australian data from GUSTO 1 (1991-3) and International Study Group r-TPA Streptokinase Mortality (1989) trials

Philip A. Tideman, Jackie K. Fabri, Philip E. Aylward, R. J. Simes

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The patterns of revascularisation with percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass graft (CABG) surgery in the GUSTO 1 trial patients in Australia are described. In comparison with rates documented in earlier trials of thrombolytic therapy in Australia, the rates of revascularisation post-thrombolysis increased by 50%, primarily due to a doubling in the rate of use of PTCA. However, the rates were low by international comparisons. There were marked variations in the rates of revascularisation between States, but no correlation with differences in mortality between States. The main predictors of post thrombolysis PTCA were prior angina, mild infarction and access to PTCA facilities.

Original languageEnglish
Pages (from-to)533-540
Number of pages8
JournalAustralian and New Zealand journal of medicine
Issue number4
Publication statusPublished - 1 Jan 1998


  • Acute myocardial infarction
  • Coronary artery bypass graft
  • Percutaneous transluminal coronary angioplasty
  • Regional variations
  • Thrombolysis

ASJC Scopus subject areas

  • Internal Medicine

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