Interindividual differences in neurobehavioral performance in response to increasing homeostatic sleep pressure

Xuan Zhou, Sally A. Ferguson, Raymond W. Matthews, Charli Sargent, David Darwent, David J. Kennaway, Gregory D. Roach

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Neurobehavioral function deteriorates with increasing homeostatic sleep pressure during wakefulness. It has been claimed that some individuals exhibit a quicker rate of such deterioration than others, thus being more vulnerable than others to the detrimental impact of increasing homeostatic sleep pressure. Evidence supporting the claim, however, has been limited by methodological issues. To overcome these limitations, the current study used a 12-calendar-day, 28-h forced desynchrony (FD) protocol (sleep:wake period1:2) to study individual differences in the rate of change in neurobehavioral performance with increasing homeostatic sleep pressure. Neurobehavioral performance was assessed with a psychomotor vigilance task and a serial addition subtraction task. A significant performance decline on both tasks was revealed within as short as 17h of wakefulness. The rates of decline of individual performance trajectories were, however, not different from the group average rate. This suggests that individuals are not differentially vulnerable to the detrimental impact of increasing homeostatic sleep pressure. copyright

Original languageEnglish
Pages (from-to)922-933
Number of pages12
JournalChronobiology International
Volume27
Issue number5
DOIs
Publication statusPublished - 1 Jun 2010
Externally publishedYes

Keywords

  • Forced desynchrony
  • Homeostatic sleep pressure
  • Interindividual differences
  • Neurobehavioural performance
  • Vulnerability

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

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