Hypertriglyceridemic waist and newly-diagnosed diabetes among remote-dwelling indigenous Australians

M. Daniel, C. Paquet, S. J. Kelly, G. Zang, K. G. Rowley, R. McDermott, K. O'Dea

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Aims: Hypertriglyceridemic waist (HTgW) is predictive of cardiovascular disease. The HTgW relationship with diabetes is little studied. Methods: This study analysed data from diabetes and cardiovascular risk factor screening programmes in remote Indigenous Australian settlements. Elevated waist girth (EW) was defined as 90 for men (1134) or 80 cm for women (n=1313). Hypertriglyceridemia (ETg) was defined as 1.7 mmol/L. Diabetes was defined as fasting plasma glucose 7.0 mmol/L. Body mass index (BMI) was categorised as <22, 22-24.9 and 25.0 kg/m2. Logistic regression was used to analyse the odds of newly-diagnosed diabetes for individuals with either HTgW, ETg or EW, relative to individuals with values below cut-offs. Results: The prevalence of HTgW was 33.2% for men and 34.8% for women. Accounting for age-group and gender, newly-diagnosed diabetes was associated (odds ratio (OR) (95% confidence interval)) with HTgW: 9.6 (6.6, 13.8). The relationship remained strong after accounting for the covariates BMI and smoking (OR =4.9 (2.7, 8.8)). In BMI-stratified analyses the strongest odds were observed for the lowest category (22 kg/m2: OR=12.9 (4.0, 41.7)). Conclusions: HTgW has a high prevalence and is associated with newly-diagnosed diabetes in Indigenous people, particularly those with BMI <22&kg/m2, whom clinicians might not normally consider for screening.

Original languageEnglish
Pages (from-to)496-504
Number of pages9
JournalAnnals of Human Biology
Volume40
Issue number6
DOIs
Publication statusPublished - 1 Nov 2013

Keywords

  • Australia
  • Diabetes
  • Hypertriglyceridemic waist
  • Indigenous people

ASJC Scopus subject areas

  • Epidemiology
  • Physiology
  • Ageing
  • Genetics
  • Public Health, Environmental and Occupational Health

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