Human multipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright,/CD34-/CD45 -/glycophorin-A- bone marrow cells

Andrew C W Zannettino, Sharon Paton, Angela Kortesidis, Fiona Khor, Silviu Itescu, Stan Gronthos

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Magnetic and flow cytometry-based methods were used to characterize clonogenic stromal cells in human bone marrow. STRO-1bright stromal cells were found to lack expression of CD34, CD45 and glycophorin-A markers associated with hematopoietic progenitor cells. These studies support the view that these are two distinct stem cell compartments in adult bone marrow.

Original languageEnglish
Pages (from-to)1707-1708
Number of pages2
JournalHaematologica
Volume92
Issue number12
DOIs
Publication statusPublished - 1 Dec 2007

Keywords

  • BMSSC
  • CD34
  • CD45
  • CFU-F
  • Glycophorin-A
  • MSC
  • STRO-1

ASJC Scopus subject areas

  • Hematology

Cite this