HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM)

P. Zimmet, P. Kiely, R. Cross, J. Court, J. Bornstein

Research output: Contribution to journalArticle

Abstract

Summary: HLA antigens were determined in 169 Australian patients with insulin dependent diabetes mellitus (IDDM). HLA‐B8 (47·9% v. 23·8%) and B15 (18·9% v. 8·2%) were significantly more frequent in the IDDM patients than in 1460 controls. The relative risks for developing IDDM in people carrying these antigens were 2·94 and 2·59 respectively. Carriers of the B8/B15 genotype had a relative risk of 5·48. These HLA associations in Australian IDDM patients are similar to those reported in other predominantly Caucasian populations.

LanguageEnglish
Pages633-636
Number of pages4
JournalAustralian and New Zealand journal of medicine
Volume9
Issue number6
DOIs
Publication statusPublished - 1 Jan 1979

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Zimmet, P. ; Kiely, P. ; Cross, R. ; Court, J. ; Bornstein, J. / HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM). In: Australian and New Zealand journal of medicine. 1979 ; Vol. 9, No. 6. pp. 633-636.
@article{a19ff55fa1f64970bb1344f7e7cfd841,
title = "HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM)",
abstract = "Summary: HLA antigens were determined in 169 Australian patients with insulin dependent diabetes mellitus (IDDM). HLA‐B8 (47·9{\%} v. 23·8{\%}) and B15 (18·9{\%} v. 8·2{\%}) were significantly more frequent in the IDDM patients than in 1460 controls. The relative risks for developing IDDM in people carrying these antigens were 2·94 and 2·59 respectively. Carriers of the B8/B15 genotype had a relative risk of 5·48. These HLA associations in Australian IDDM patients are similar to those reported in other predominantly Caucasian populations.",
author = "P. Zimmet and P. Kiely and R. Cross and J. Court and J. Bornstein",
year = "1979",
month = "1",
day = "1",
doi = "10.1111/j.1445-5994.1979.tb04191.x",
language = "English",
volume = "9",
pages = "633--636",
journal = "Australian and New Zealand Journal of Medicine",
issn = "1444-0903",
publisher = "Wiley-Blackwell",
number = "6",

}

HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM). / Zimmet, P.; Kiely, P.; Cross, R.; Court, J.; Bornstein, J.

In: Australian and New Zealand journal of medicine, Vol. 9, No. 6, 01.01.1979, p. 633-636.

Research output: Contribution to journalArticle

TY - JOUR

T1 - HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM)

AU - Zimmet, P.

AU - Kiely, P.

AU - Cross, R.

AU - Court, J.

AU - Bornstein, J.

PY - 1979/1/1

Y1 - 1979/1/1

N2 - Summary: HLA antigens were determined in 169 Australian patients with insulin dependent diabetes mellitus (IDDM). HLA‐B8 (47·9% v. 23·8%) and B15 (18·9% v. 8·2%) were significantly more frequent in the IDDM patients than in 1460 controls. The relative risks for developing IDDM in people carrying these antigens were 2·94 and 2·59 respectively. Carriers of the B8/B15 genotype had a relative risk of 5·48. These HLA associations in Australian IDDM patients are similar to those reported in other predominantly Caucasian populations.

AB - Summary: HLA antigens were determined in 169 Australian patients with insulin dependent diabetes mellitus (IDDM). HLA‐B8 (47·9% v. 23·8%) and B15 (18·9% v. 8·2%) were significantly more frequent in the IDDM patients than in 1460 controls. The relative risks for developing IDDM in people carrying these antigens were 2·94 and 2·59 respectively. Carriers of the B8/B15 genotype had a relative risk of 5·48. These HLA associations in Australian IDDM patients are similar to those reported in other predominantly Caucasian populations.

UR - http://www.scopus.com/inward/record.url?scp=0018570143&partnerID=8YFLogxK

U2 - 10.1111/j.1445-5994.1979.tb04191.x

DO - 10.1111/j.1445-5994.1979.tb04191.x

M3 - Article

VL - 9

SP - 633

EP - 636

JO - Australian and New Zealand Journal of Medicine

T2 - Australian and New Zealand Journal of Medicine

JF - Australian and New Zealand Journal of Medicine

SN - 1444-0903

IS - 6

ER -