Higher protein and energy intake is associated with increased weight gain in pre-term infants

Carmel T. Collins, Mei Chien Chua, Victor S. Rajadurai, Andrew J. McPhee, Lisa N. Miller, Robert A. Gibson, Maria Makrides

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Aim: To characterise and compare the nutritional management and growth in infants <33 weeks' gestation in two tertiary centres. Methods: An audit of daily intake and growth from birth to discharge home was undertaken in two neonatal units: The KK Women's and Children's Hospital Singapore and the Adelaide Women's and Children's Hospital, South Australia. Mixed models were used to model intake and daily weight (g/day) accounting for repeated day per subject. Results: The clinical characteristics of the two cohorts were similar. The Adelaide cohort had a higher initial energy intake in the first 5 days compared with the Singapore cohort, and a significantly greater weekly increase of 21.0 kcal/week (95% CI 7.7-34.3; P = 0.002). The Adelaide cohort also had a higher initial protein intake and a significantly greater weekly increase of 0.88 g/week (95% CI 0.5, 1.3), P < 0.001) compared with the Singapore cohort. The weight gain of the Adelaide cohort was 9 g/day more than the Singapore cohort (95% CI 7.3, 10.7; P < 0.001). Post-natal growth failure was evident in 32% (n = 64) of the Adelaide cohort and 64% (n = 94) of the Singapore cohort. Conclusions: The two centres showed distinct differences in nutritional management. A higher energy and protein intake was associated with improved growth yet growth in both cohorts was still below current recommendations. 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

Original languageEnglish
Pages (from-to)96-102
Number of pages7
JournalJournal of Paediatrics and Child Health
Volume46
Issue number3
DOIs
Publication statusPublished or Issued - 1 Mar 2010
Externally publishedYes

Keywords

  • Enteral nutrition
  • Infant
  • Parenteral nutrition
  • Premature

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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