High amylose starch on bowel function, insulin sensitivity and lipids

P. J. Nestel, M. Noakes, P. Clifton, G. McIntosh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We evaluated the effects of a high carbohydrate diet which was enriched either in high-amylose starch, low-amylose starch or oatbran. 23 overweight subjects with insulin resistance ate the 3 diets for 4 weeks each, in random, blinded, cross-over design. No effects were seen on fasting plasma lipids, glucose or insulin However when the 2 starches (incorporated within processed, cooked foods) were compared after single meals, glycemia and insulin response were significantly less with high amylose (high resistant starch). Both oatbran and high amylose starch decreased fecal pH and secondary bile acids; only high amylose starch increased fecal volatile fatty acids especially butyrate by 32% (p<0.001) High amylose starch (in bread, pasta and breakfast cereal) therefore dampened insulin hyperresponsiveness (p<0.02) and changed large bowel environment into one that may inhibit malignancy.

Original languageEnglish
JournalFASEB Journal
Volume10
Issue number3
Publication statusPublished - 1996
Externally publishedYes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

Cite this

Nestel, P. J., Noakes, M., Clifton, P., & McIntosh, G. (1996). High amylose starch on bowel function, insulin sensitivity and lipids. FASEB Journal, 10(3).