Gastrointestinal mechanosensory function in health and disease

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

The gastrointestinal (GI) tract has a multitude of roles including ingestion; digestion of food; absorption of nutrients and water; elimination of waste; and defense against toxins, antigens, and pathogens. To meet these challenges, there is an elaborate sensory system, with distinct chemo- and mechanosensory modalities, that monitors the various processes along the GI tract, providing feedback and maintaining physiological function. This chapter will focus on physiological and pathophysiological mechanosensory processes within the wall of the gut and along the whole length of the GI tract.

Original languageEnglish
Title of host publicationMechanobiology in Health and Disease
PublisherElsevier
Pages377-414
Number of pages38
ISBN (Electronic)9780128129524
ISBN (Print)9780128129531
DOIs
Publication statusPublished or Issued - 1 Jan 2018

Keywords

  • Enteric nervous system
  • Enterochromaffin cells
  • Gastrointestinal tract
  • Interstitial cells of cajal
  • Mechanosensation
  • Obesity
  • Pain
  • Smooth muscle cells
  • Spinal afferents
  • Vagal afferents

ASJC Scopus subject areas

  • Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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