Frequency and distribution of deletions in dystrophin gene in Duchenne muscular dystrophy patients from an east-European Slavonic population.

L. Kádasi, J. Gécz, L. Saksová

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Abstract

In 32 unrelated DMD patients originating from Slovakia (Czechoslovakia), screening for deletions in the dystrophin gene was performed with cDNA probes Cf56a, Cf56b, 1-2a, 2b-3 4-5a, 5b-7, and 8. In 14 out of 32 DMD patients (43.75 per cent), a deletion extending from one to three adjacent probes was observed. The highest proportion of deletions was found with probes 8 and 1-2a (50 and 28.6 per cent of all deletions, respectively). All these proportions are similar to those found in other populations of European origin.

Original languageEnglish
Pages (from-to)137-140
Number of pages4
JournalGene geography : a computerized bulletin on human gene frequencies
Volume5
Issue number3
Publication statusPublished - 1 Jan 1991
Externally publishedYes

ASJC Scopus subject areas

  • Genetics(clinical)

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