Factors influencing reported rates of treated end-stage renal disease

Stephen McDonald, Margaret McCredie, Sheila Williams, John Stewart

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Rates of treated end-stage renal disease have risen relentlessly throughout the Western world over the past 30 years, with little indication of a slowing in the rate. This increase has a number of causes, such as important trends in disease prevalence, changing population structure, and changing treatment patterns. A number of biases also affect measured rates of renal replacement therapy. These biases include lead-time and length bias, as well as classification bias. A further important effect will be changes in competing risks, in particular, changing mortality from cardiovascular disease. We examine the effects of these factors by analyzing data from the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry. Rates of treated ESRD have risen steadily over the past 30 years, which appears to be the result of several factors. Rates among older people have increased particularly, as have rates among Australian and New Zealand indigenous peoples. Higher rates are also seen among some immigrant groups. Accentuating the effect of these changing rates are changes in the structure of the population and the tendency to commence treatment earlier.The increase in rates of ESRD treatment is often ascribed to an explosion of kidney disease. Although a major contribution comes from increasing disease prevalence, understanding the implications of this increase requires comprehension of a number of other factors.

LanguageEnglish
Pages32-38
Number of pages7
JournalAdvances in Chronic Kidney Disease
Volume12
Issue number1
DOIs
Publication statusPublished - 1 Jan 2005
Externally publishedYes

Keywords

  • Registry
  • bias
  • end-stage renal disease
  • renal replacement therapy

ASJC Scopus subject areas

  • Nephrology

Cite this

McDonald, Stephen ; McCredie, Margaret ; Williams, Sheila ; Stewart, John. / Factors influencing reported rates of treated end-stage renal disease. In: Advances in Chronic Kidney Disease. 2005 ; Vol. 12, No. 1. pp. 32-38.
@article{088108ea594549f3b36eca4dab62c1cf,
title = "Factors influencing reported rates of treated end-stage renal disease",
abstract = "Rates of treated end-stage renal disease have risen relentlessly throughout the Western world over the past 30 years, with little indication of a slowing in the rate. This increase has a number of causes, such as important trends in disease prevalence, changing population structure, and changing treatment patterns. A number of biases also affect measured rates of renal replacement therapy. These biases include lead-time and length bias, as well as classification bias. A further important effect will be changes in competing risks, in particular, changing mortality from cardiovascular disease. We examine the effects of these factors by analyzing data from the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry. Rates of treated ESRD have risen steadily over the past 30 years, which appears to be the result of several factors. Rates among older people have increased particularly, as have rates among Australian and New Zealand indigenous peoples. Higher rates are also seen among some immigrant groups. Accentuating the effect of these changing rates are changes in the structure of the population and the tendency to commence treatment earlier.The increase in rates of ESRD treatment is often ascribed to an explosion of kidney disease. Although a major contribution comes from increasing disease prevalence, understanding the implications of this increase requires comprehension of a number of other factors.",
keywords = "Registry, bias, end-stage renal disease, renal replacement therapy",
author = "Stephen McDonald and Margaret McCredie and Sheila Williams and John Stewart",
year = "2005",
month = "1",
day = "1",
doi = "10.1053/j.ackd.2004.10.011",
language = "English",
volume = "12",
pages = "32--38",
journal = "Advances in Chronic Kidney Disease",
issn = "1548-5595",
publisher = "W.B. Saunders Ltd",
number = "1",

}

Factors influencing reported rates of treated end-stage renal disease. / McDonald, Stephen; McCredie, Margaret; Williams, Sheila; Stewart, John.

In: Advances in Chronic Kidney Disease, Vol. 12, No. 1, 01.01.2005, p. 32-38.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Factors influencing reported rates of treated end-stage renal disease

AU - McDonald, Stephen

AU - McCredie, Margaret

AU - Williams, Sheila

AU - Stewart, John

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Rates of treated end-stage renal disease have risen relentlessly throughout the Western world over the past 30 years, with little indication of a slowing in the rate. This increase has a number of causes, such as important trends in disease prevalence, changing population structure, and changing treatment patterns. A number of biases also affect measured rates of renal replacement therapy. These biases include lead-time and length bias, as well as classification bias. A further important effect will be changes in competing risks, in particular, changing mortality from cardiovascular disease. We examine the effects of these factors by analyzing data from the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry. Rates of treated ESRD have risen steadily over the past 30 years, which appears to be the result of several factors. Rates among older people have increased particularly, as have rates among Australian and New Zealand indigenous peoples. Higher rates are also seen among some immigrant groups. Accentuating the effect of these changing rates are changes in the structure of the population and the tendency to commence treatment earlier.The increase in rates of ESRD treatment is often ascribed to an explosion of kidney disease. Although a major contribution comes from increasing disease prevalence, understanding the implications of this increase requires comprehension of a number of other factors.

AB - Rates of treated end-stage renal disease have risen relentlessly throughout the Western world over the past 30 years, with little indication of a slowing in the rate. This increase has a number of causes, such as important trends in disease prevalence, changing population structure, and changing treatment patterns. A number of biases also affect measured rates of renal replacement therapy. These biases include lead-time and length bias, as well as classification bias. A further important effect will be changes in competing risks, in particular, changing mortality from cardiovascular disease. We examine the effects of these factors by analyzing data from the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry. Rates of treated ESRD have risen steadily over the past 30 years, which appears to be the result of several factors. Rates among older people have increased particularly, as have rates among Australian and New Zealand indigenous peoples. Higher rates are also seen among some immigrant groups. Accentuating the effect of these changing rates are changes in the structure of the population and the tendency to commence treatment earlier.The increase in rates of ESRD treatment is often ascribed to an explosion of kidney disease. Although a major contribution comes from increasing disease prevalence, understanding the implications of this increase requires comprehension of a number of other factors.

KW - Registry

KW - bias

KW - end-stage renal disease

KW - renal replacement therapy

UR - http://www.scopus.com/inward/record.url?scp=13844281412&partnerID=8YFLogxK

U2 - 10.1053/j.ackd.2004.10.011

DO - 10.1053/j.ackd.2004.10.011

M3 - Article

VL - 12

SP - 32

EP - 38

JO - Advances in Chronic Kidney Disease

T2 - Advances in Chronic Kidney Disease

JF - Advances in Chronic Kidney Disease

SN - 1548-5595

IS - 1

ER -