Energy Adaptations Persist 2 Years After Sleeve Gastrectomy and Gastric Bypass

Charmaine S. Tam, Georgia Rigas, Leonie Heilbronn, Tania Matisan, Yasmine Probst, Michael Talbot

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Non-surgical weight loss induces a greater than expected decrease in energy expenditure, a phenomenon known as ‘metabolic adaptation’. The effects of different bariatric surgery procedures on metabolic adaptation are not yet known and may partially contribute to weight loss success. We compared resting energy expenditure (REE) in 35 subjects (nine males; age = 46 ± 11 years; BMI = 42.1 ± 6.5 kg/m2) undergoing gastric band, sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) up to 2 years after surgery. We found a greater than expected reduction of 130–300 kcal/day at 6 weeks after sleeve and bypass surgery which was not explained by changes in body composition; this change was not seen in the band group. The suppression in REE after sleeve and RYGB remained up to 2 years, even after weight loss had plateaued. Our findings suggest that energy adaptation is not a contributing mechanism to medium-term weight maintenance after sleeve and RYGB bariatric surgeries.

Original languageEnglish
Pages (from-to)459-463
Number of pages5
JournalObesity Surgery
Volume26
Issue number2
DOIs
Publication statusPublished or Issued - 1 Feb 2016

Keywords

  • Energy expenditure
  • Metabolic adaptation
  • Resting metabolic rate

ASJC Scopus subject areas

  • Surgery
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

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