Effectiveness of intrauterine insemination in subfertile couples with an isolated cervical factor: a randomized clinical trial

Pieternel Steures, Jan Willem van der Steeg, Peter G A Hompes, Patrick M M Bossuyt, J. Dik F Habbema, Marinus J C Eijkemans, Willem A. Schöls, Jan M. Burggraaff, Fulco van der Veen, Ben W J Mol

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29 Citations (Scopus)


After randomization of subfertile couples with an isolated cervical factor to intrauterine insemination for 6 months or expectant management for 6 months, 26 women (51%) vs. 16 women (33%) conceived, respectively. Of these pregnancies, 22 (43%) vs. 13 (27%) were ongoing (relative risk, 1.6; 95% confidence interval, 0.91 to 2.8). There was one multiple pregnancy in the group that was allocated to intrauterine insemination. This trial suggests a beneficial effect of IUI in couples with an isolated cervical factor.

Original languageEnglish
Pages (from-to)1692-1696
Number of pages5
JournalFertility and Sterility
Issue number6
Publication statusPublished or Issued - Dec 2007

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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