TY - JOUR
T1 - Effectiveness of Bivalirudin as a replacement for Heparin during cardiopulmonary bypass in patients undergoing coronary artery bypass grafting
AU - Koster, Andreas
AU - Spiess, Bruce
AU - Chew, Derek P.
AU - Krabatsch, Thomas
AU - Tambeur, Luc
AU - Deanda, Abe
AU - Hetzer, Roland
AU - Kuppe, Hermann
AU - Smedira, Nicholas G.
AU - Lincoff, A. Michael
PY - 2004/2/1
Y1 - 2004/2/1
N2 - We investigated the use of bivalirudin as an anticoagulant therapy during cardiopulmonary bypass in 20 patients who underwent coronary artery bypass grafting. Primary end points consisted of clinical outcome data, whereas secondary end points focused on blood loss, transfusions, pharmacokinetics, and monitoring. Our data provide the first evidence of clinical feasibility of anticoagulation with bivalirudin during cardiopulmonary bypass.
AB - We investigated the use of bivalirudin as an anticoagulant therapy during cardiopulmonary bypass in 20 patients who underwent coronary artery bypass grafting. Primary end points consisted of clinical outcome data, whereas secondary end points focused on blood loss, transfusions, pharmacokinetics, and monitoring. Our data provide the first evidence of clinical feasibility of anticoagulation with bivalirudin during cardiopulmonary bypass.
UR - http://www.scopus.com/inward/record.url?scp=10744225946&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2003.10.021
DO - 10.1016/j.amjcard.2003.10.021
M3 - Article
C2 - 14759391
AN - SCOPUS:10744225946
VL - 93
SP - 356
EP - 359
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 3
ER -