Effect on plasma lipids of interesterifying a mix of edible oils1-3

Paul J. Nestel, Manny Noakes, G. Bryan Belling, Rosemary McArthur, Peter M. Clifton

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

The aim was to establish whether interesterification of oils, an alternative to the use of trans fatty acids in margarine manufacture, adversely affects plasma lipids. Twenty-seven hypercholesterolemic men participated in a double-blind, crossover trial of three margarines: 1) high-linoleic acid, moderate trans fatty acids; 2) high-palm oil blend (predominantly lauric, myristic, palmitic, oleic, and linoleic acids); and 3) an interesterified form of the high-palm oil margarine. Both high-palm oil margarines led to similar low-density-lipoprotein (LDL) cholesterol concentrations (4.43 ± 0.94 and 4.54 ± 0.88 mmol/L, respectively), which were significantly higher than the LDL concentrations after the high-linoleic acid margarine (4.02 ± 0.85 mmol/L, P < 0.001). Interesterification transferred substantial proportions of palmitic acid into the sn-2 position of glycerides and unsaturated fatty acids into the in-1,3 positions, and this was reflected in plasma chylomicrons. This study shows that interesterification of oils used to harden margarines does not raise plasma cholesterol more than does the margarine's constituent fatty acids.

LanguageEnglish
Pages950-955
Number of pages6
JournalAmerican Journal of Clinical Nutrition
Volume62
Issue number5
Publication statusPublished - Nov 1995
Externally publishedYes

Keywords

  • Chylomicrons
  • Fatty acids
  • Interesterification
  • Low-density-lipoprotein cholesterol

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

Nestel, P. J., Noakes, M., Belling, G. B., McArthur, R., & Clifton, P. M. (1995). Effect on plasma lipids of interesterifying a mix of edible oils1-3 . American Journal of Clinical Nutrition, 62(5), 950-955.
Nestel, Paul J. ; Noakes, Manny ; Belling, G. Bryan ; McArthur, Rosemary ; Clifton, Peter M. / Effect on plasma lipids of interesterifying a mix of edible oils1-3 . In: American Journal of Clinical Nutrition. 1995 ; Vol. 62, No. 5. pp. 950-955.
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Nestel, PJ, Noakes, M, Belling, GB, McArthur, R & Clifton, PM 1995, 'Effect on plasma lipids of interesterifying a mix of edible oils1-3 ', American Journal of Clinical Nutrition, vol. 62, no. 5, pp. 950-955.

Effect on plasma lipids of interesterifying a mix of edible oils1-3 . / Nestel, Paul J.; Noakes, Manny; Belling, G. Bryan; McArthur, Rosemary; Clifton, Peter M.

In: American Journal of Clinical Nutrition, Vol. 62, No. 5, 11.1995, p. 950-955.

Research output: Contribution to journalArticle

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Nestel PJ, Noakes M, Belling GB, McArthur R, Clifton PM. Effect on plasma lipids of interesterifying a mix of edible oils1-3 . American Journal of Clinical Nutrition. 1995 Nov;62(5):950-955.