Early-life nutritional exposures and lifelong health: Immediate and long-lasting impacts of probiotics, vitamin D, and breastfeeding

Cristiana Berti, Carlo Agostoni, Riccardo Davanzo, Elina Hyppönen, Erika Isolauri, Helle M. Meltzer, Régine P.M. Steegers-Theunissen, Irene Cetin

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Pregnancy and infancy comprise the most critical stages for conditioning an individual's health, with a number of implications for subsequent risks of morbidity, mortality, and reproductive health. Nutrition may influence both the overall pregnancy outcome and the growth trajectory and immune system of the fetus and infant, with short- and long-term effects on the health of the offspring. Within this context, leading experts at Expo Milano 2015 in Milan, Italy, discussed up-to-date knowledge while providing suggestions and challenges before, during, and after pregnancy. This narrative review summarizes the key issues raised by the experts concerning the interplay between the nutritional environment from conception to early infancy and the offspring's immediate and lifelong health, with a particular focus on epigenetic mechanisms, probiotics, vitamin D, and breastfeeding. Taken together, the findings strengthen the awareness that nutritional exposures occurring from preconception to the postnatal period may be strong determinants of the offspring's health and may provide supportive evidence for current nutritional recommendations and guidelines for pregnant women and infants. Critical topics to be addressed in future research and translated into recommendations of public health relevance are also highlighted.

LanguageEnglish
Article numbernuw056
Pages83-97
Number of pages15
JournalNutrition Reviews
Volume75
Issue number2
DOIs
Publication statusPublished - 1 Feb 2017

Keywords

  • Epigenetics
  • Gut microbiota
  • Infancy
  • Nutrition
  • Pregnancy

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Berti, Cristiana ; Agostoni, Carlo ; Davanzo, Riccardo ; Hyppönen, Elina ; Isolauri, Erika ; Meltzer, Helle M. ; Steegers-Theunissen, Régine P.M. ; Cetin, Irene. / Early-life nutritional exposures and lifelong health : Immediate and long-lasting impacts of probiotics, vitamin D, and breastfeeding. In: Nutrition Reviews. 2017 ; Vol. 75, No. 2. pp. 83-97.
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Berti, C, Agostoni, C, Davanzo, R, Hyppönen, E, Isolauri, E, Meltzer, HM, Steegers-Theunissen, RPM & Cetin, I 2017, 'Early-life nutritional exposures and lifelong health: Immediate and long-lasting impacts of probiotics, vitamin D, and breastfeeding', Nutrition Reviews, vol. 75, no. 2, nuw056, pp. 83-97. https://doi.org/10.1093/nutrit/nuw056

Early-life nutritional exposures and lifelong health : Immediate and long-lasting impacts of probiotics, vitamin D, and breastfeeding. / Berti, Cristiana; Agostoni, Carlo; Davanzo, Riccardo; Hyppönen, Elina; Isolauri, Erika; Meltzer, Helle M.; Steegers-Theunissen, Régine P.M.; Cetin, Irene.

In: Nutrition Reviews, Vol. 75, No. 2, nuw056, 01.02.2017, p. 83-97.

Research output: Contribution to journalArticle

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