Dental Pulp Stem Cells

He Liu, Stan Gronthos, Songtao Shi

Research output: Contribution to journalReview article

81 Citations (Scopus)

Abstract

Postnatal stem cells have been isolated from a variety of tissues. These stem cells are thought to possess great therapeutic potential for repairing damaged and/or defective tissues. Clinically, hematopoietic stem cells have been successfully used for decades in the treatment of various diseases and disorders. However, the therapeutic potential of other postnatal stem cell populations has yet to be realized, because of the lack of detailed understanding of their stem cell characteristics at the cellular and molecular levels. Furthermore, there is limited knowledge of their therapeutic value at the preclinical level. Therefore, it is necessary to develop optimal strategies and approaches to overcome the substantial challenges currently faced by researchers examining the clinical efficacy of different postnatal stem cell populations. In this review, we introduce methodologies for isolating postnatal stem cells from human dental pulp and discuss their potential role in tissue regeneration.

Original languageEnglish
Pages (from-to)99-113
Number of pages15
JournalMethods in Enzymology
Volume419
DOIs
Publication statusPublished - 2006
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry

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