Degradation of human cartilage by monocytes

L. M. Kumaratilake; I. C. Kowanko; E. J. Bates; A. Ferrante

doi:10.1016/0165-2478(90)90006-C

Degradation of human cartilage by monocytes

L. M. Kumaratilake, I. C. Kowanko, E. J. Bates, A. Ferrante

Research output: Contribution to journal › Article › peer-review

Abstract

The effect of human peripheral blood monocytes on the degradation of human articular cartilage was studied in vitro using a radiometric assay to detect proteoglycan breakdown. The results showed that proteoglycan breakdown was increased by 60% after a 20 h exposure to monocytes (p<0.001).

Original language	English
Pages (from-to)	243-245
Number of pages	3
Journal	Immunology Letters
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/0165-2478(90)90006-C
Publication status	Published - 1 Jan 1990
Externally published	Yes

Keywords

Cartilage damage
Monocyte
Proteoglycan

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Access to Document

10.1016/0165-2478(90)90006-C

Link to publication in Scopus

Cite this

@article{19219f6e74714ae4b0629748ae5c2a7f,

title = "Degradation of human cartilage by monocytes",

abstract = "The effect of human peripheral blood monocytes on the degradation of human articular cartilage was studied in vitro using a radiometric assay to detect proteoglycan breakdown. The results showed that proteoglycan breakdown was increased by 60% after a 20 h exposure to monocytes (p<0.001).",

keywords = "Cartilage damage, Monocyte, Proteoglycan",

author = "Kumaratilake, {L. M.} and Kowanko, {I. C.} and Bates, {E. J.} and A. Ferrante",

year = "1990",

month = jan,

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journal = "Immunology Letters",

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AU - Kumaratilake, L. M.

AU - Kowanko, I. C.

AU - Bates, E. J.

AU - Ferrante, A.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - The effect of human peripheral blood monocytes on the degradation of human articular cartilage was studied in vitro using a radiometric assay to detect proteoglycan breakdown. The results showed that proteoglycan breakdown was increased by 60% after a 20 h exposure to monocytes (p<0.001).

AB - The effect of human peripheral blood monocytes on the degradation of human articular cartilage was studied in vitro using a radiometric assay to detect proteoglycan breakdown. The results showed that proteoglycan breakdown was increased by 60% after a 20 h exposure to monocytes (p<0.001).

KW - Cartilage damage

KW - Monocyte

KW - Proteoglycan

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DO - 10.1016/0165-2478(90)90006-C

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JF - Immunology Letters

SN - 0165-2478

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