Degradation of human cartilage by monocytes

L. M. Kumaratilake, I. C. Kowanko, E. J. Bates, A. Ferrante

Research output: Contribution to journal › Article

Abstract

The effect of human peripheral blood monocytes on the degradation of human articular cartilage was studied in vitro using a radiometric assay to detect proteoglycan breakdown. The results showed that proteoglycan breakdown was increased by 60% after a 20 h exposure to monocytes (p<0.001).

Original languageEnglish
Pages (from-to)243-245
Number of pages3
JournalImmunology Letters
Volume24
Issue number4
DOIs
Publication statusPublished - 1 Jan 1990
Externally publishedYes

Keywords

  • Cartilage damage
  • Monocyte
  • Proteoglycan

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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Kumaratilake, L. M., Kowanko, I. C., Bates, E. J., & Ferrante, A. (1990). Degradation of human cartilage by monocytes. Immunology Letters, 24(4), 243-245. https://doi.org/10.1016/0165-2478(90)90006-C