Degradation of human cartilage by monocytes

L. M. Kumaratilake, I. C. Kowanko, E. J. Bates, A. Ferrante

Research output: Contribution to journalArticlepeer-review


The effect of human peripheral blood monocytes on the degradation of human articular cartilage was studied in vitro using a radiometric assay to detect proteoglycan breakdown. The results showed that proteoglycan breakdown was increased by 60% after a 20 h exposure to monocytes (p<0.001).

Original languageEnglish
Pages (from-to)243-245
Number of pages3
JournalImmunology Letters
Issue number4
Publication statusPublished - 1 Jan 1990
Externally publishedYes


  • Cartilage damage
  • Monocyte
  • Proteoglycan

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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