Decreased glucose utilisation does not increase food intake in the marsupial Sminthopsis crassicaudata

Perdita J. Hope, Gary A. Wittert, Ian Chapman, John Morley, Michael Horowitz

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The marsupial Sminthopsis crassicaudata increases food intake following a fast. However, the role of metabolic fuel availability, in particular glucose, in the regulation of food intake in this animal is unknown. In this study, we have demonstrated that neither insulin-induced hypoglycaemia nor metabolic blockade of glucose utilisation with 2-deoxy-D-glucose effects food intake compared to saline-treated controls, suggesting that mechanisms other than glucose availability are important in the regulation of food intake in this marsupial. These data are discussed in the context of the role of glucoprivation in feeding in other mammals.

Original languageEnglish
Pages (from-to)31-34
Number of pages4
JournalPhysiology and Behavior
Volume63
Issue number1
DOIs
Publication statusPublished or Issued - 31 Dec 1997

Keywords

  • 2-Deoxy-D-glucose
  • Glucoprivation
  • Hypoglycaemia
  • Insulin
  • Marsupial
  • Sminthopsis crassicaudata

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

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