Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults

Terence Dwyer, Costan G. Magnussen, Michael D. Schmidt, Obioha C. Ukoumunne, Anne Louise Ponsonby, Olli T. Raitakari, Paul Zimmet, Steven N. Blair, Russell Thomson, Verityj Cleland, Alison Venn

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

OBJECTIVE - To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance. RESEARCH DESIGN AND METHODS - A prospective cohort study set in Australia in 2004-2006 followed up a cohort of 647 adults who had participated in the Australian Schools Health and Fitness Survey in 1985 and who had undergone anthropometry and cardiorespiratory fitness assessment during the survey. Outcome measures were insulin resistance and obesity, defined as a homeostasis model assessment index above the 75th sex-specific percentile and BMI≥ 30 kg/m 2, respectively. RESULTS - Lower levels of child cardiorespiratory fitness were associated with increased odds of adult obesity (adjusted odds ratio [OR] per unit decrease 3.0 [95% CI 1.6-5.6]) and insulin resistance (1.7 [1.1-2.6]). A decline in fitness level between childhood and adulthood was associated with increased obesity (4.5 [2.6-7.7]) and insulin resistance (2.1 [1.5-2.9]) per unit decline. CONCLUSIONS - A decline in fitness from childhood to adulthood, and by inference a decline in physical activity, is associated with obesity and insulin resistance in adulthood. Programs aimed at maintaining high childhood physical activity levels into adulthood may have potential for reducing the burden of obesity and type 2 diabetes in adults.

LanguageEnglish
Pages683-687
Number of pages5
JournalDiabetes Care
Volume32
Issue number4
DOIs
Publication statusPublished - 1 Apr 2009

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialised Nursing

Cite this

Dwyer, T., Magnussen, C. G., Schmidt, M. D., Ukoumunne, O. C., Ponsonby, A. L., Raitakari, O. T., ... Venn, A. (2009). Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults. Diabetes Care, 32(4), 683-687. https://doi.org/10.2337/dc08-1638
Dwyer, Terence ; Magnussen, Costan G. ; Schmidt, Michael D. ; Ukoumunne, Obioha C. ; Ponsonby, Anne Louise ; Raitakari, Olli T. ; Zimmet, Paul ; Blair, Steven N. ; Thomson, Russell ; Cleland, Verityj ; Venn, Alison. / Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults. In: Diabetes Care. 2009 ; Vol. 32, No. 4. pp. 683-687.
@article{fd6ea4207ab847f3ad07caffd8d5f093,
title = "Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults",
abstract = "OBJECTIVE - To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance. RESEARCH DESIGN AND METHODS - A prospective cohort study set in Australia in 2004-2006 followed up a cohort of 647 adults who had participated in the Australian Schools Health and Fitness Survey in 1985 and who had undergone anthropometry and cardiorespiratory fitness assessment during the survey. Outcome measures were insulin resistance and obesity, defined as a homeostasis model assessment index above the 75th sex-specific percentile and BMI≥ 30 kg/m 2, respectively. RESULTS - Lower levels of child cardiorespiratory fitness were associated with increased odds of adult obesity (adjusted odds ratio [OR] per unit decrease 3.0 [95{\%} CI 1.6-5.6]) and insulin resistance (1.7 [1.1-2.6]). A decline in fitness level between childhood and adulthood was associated with increased obesity (4.5 [2.6-7.7]) and insulin resistance (2.1 [1.5-2.9]) per unit decline. CONCLUSIONS - A decline in fitness from childhood to adulthood, and by inference a decline in physical activity, is associated with obesity and insulin resistance in adulthood. Programs aimed at maintaining high childhood physical activity levels into adulthood may have potential for reducing the burden of obesity and type 2 diabetes in adults.",
author = "Terence Dwyer and Magnussen, {Costan G.} and Schmidt, {Michael D.} and Ukoumunne, {Obioha C.} and Ponsonby, {Anne Louise} and Raitakari, {Olli T.} and Paul Zimmet and Blair, {Steven N.} and Russell Thomson and Verityj Cleland and Alison Venn",
year = "2009",
month = "4",
day = "1",
doi = "10.2337/dc08-1638",
language = "English",
volume = "32",
pages = "683--687",
journal = "Diabetes Care",
issn = "0149-5992",
publisher = "American Diabetes Association Inc.",
number = "4",

}

Dwyer, T, Magnussen, CG, Schmidt, MD, Ukoumunne, OC, Ponsonby, AL, Raitakari, OT, Zimmet, P, Blair, SN, Thomson, R, Cleland, V & Venn, A 2009, 'Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults', Diabetes Care, vol. 32, no. 4, pp. 683-687. https://doi.org/10.2337/dc08-1638

Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults. / Dwyer, Terence; Magnussen, Costan G.; Schmidt, Michael D.; Ukoumunne, Obioha C.; Ponsonby, Anne Louise; Raitakari, Olli T.; Zimmet, Paul; Blair, Steven N.; Thomson, Russell; Cleland, Verityj; Venn, Alison.

In: Diabetes Care, Vol. 32, No. 4, 01.04.2009, p. 683-687.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults

AU - Dwyer, Terence

AU - Magnussen, Costan G.

AU - Schmidt, Michael D.

AU - Ukoumunne, Obioha C.

AU - Ponsonby, Anne Louise

AU - Raitakari, Olli T.

AU - Zimmet, Paul

AU - Blair, Steven N.

AU - Thomson, Russell

AU - Cleland, Verityj

AU - Venn, Alison

PY - 2009/4/1

Y1 - 2009/4/1

N2 - OBJECTIVE - To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance. RESEARCH DESIGN AND METHODS - A prospective cohort study set in Australia in 2004-2006 followed up a cohort of 647 adults who had participated in the Australian Schools Health and Fitness Survey in 1985 and who had undergone anthropometry and cardiorespiratory fitness assessment during the survey. Outcome measures were insulin resistance and obesity, defined as a homeostasis model assessment index above the 75th sex-specific percentile and BMI≥ 30 kg/m 2, respectively. RESULTS - Lower levels of child cardiorespiratory fitness were associated with increased odds of adult obesity (adjusted odds ratio [OR] per unit decrease 3.0 [95% CI 1.6-5.6]) and insulin resistance (1.7 [1.1-2.6]). A decline in fitness level between childhood and adulthood was associated with increased obesity (4.5 [2.6-7.7]) and insulin resistance (2.1 [1.5-2.9]) per unit decline. CONCLUSIONS - A decline in fitness from childhood to adulthood, and by inference a decline in physical activity, is associated with obesity and insulin resistance in adulthood. Programs aimed at maintaining high childhood physical activity levels into adulthood may have potential for reducing the burden of obesity and type 2 diabetes in adults.

AB - OBJECTIVE - To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance. RESEARCH DESIGN AND METHODS - A prospective cohort study set in Australia in 2004-2006 followed up a cohort of 647 adults who had participated in the Australian Schools Health and Fitness Survey in 1985 and who had undergone anthropometry and cardiorespiratory fitness assessment during the survey. Outcome measures were insulin resistance and obesity, defined as a homeostasis model assessment index above the 75th sex-specific percentile and BMI≥ 30 kg/m 2, respectively. RESULTS - Lower levels of child cardiorespiratory fitness were associated with increased odds of adult obesity (adjusted odds ratio [OR] per unit decrease 3.0 [95% CI 1.6-5.6]) and insulin resistance (1.7 [1.1-2.6]). A decline in fitness level between childhood and adulthood was associated with increased obesity (4.5 [2.6-7.7]) and insulin resistance (2.1 [1.5-2.9]) per unit decline. CONCLUSIONS - A decline in fitness from childhood to adulthood, and by inference a decline in physical activity, is associated with obesity and insulin resistance in adulthood. Programs aimed at maintaining high childhood physical activity levels into adulthood may have potential for reducing the burden of obesity and type 2 diabetes in adults.

UR - http://www.scopus.com/inward/record.url?scp=65349135843&partnerID=8YFLogxK

U2 - 10.2337/dc08-1638

DO - 10.2337/dc08-1638

M3 - Article

VL - 32

SP - 683

EP - 687

JO - Diabetes Care

T2 - Diabetes Care

JF - Diabetes Care

SN - 0149-5992

IS - 4

ER -

Dwyer T, Magnussen CG, Schmidt MD, Ukoumunne OC, Ponsonby AL, Raitakari OT et al. Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults. Diabetes Care. 2009 Apr 1;32(4):683-687. https://doi.org/10.2337/dc08-1638