Current controversies in the use of haemoglobin A 1c

M. J L Hare, J. E. Shaw, P. Z. Zimmet

Research output: Contribution to journalReview articlepeer-review

78 Citations (Scopus)


Haemoglobin A 1c (HbA 1c) has recently been adopted by the World Health Organization into its recommended criteria for diabetes diagnosis. Much debate continues regarding the relative benefits and potential disadvantages surrounding the use of HbA 1c for this purpose. There is a lack of consensus as to whether this alteration to the definition of diabetes is a step forward or whether it could add further confusion and ambiguity to the debate on the method and criteria for the diagnosis of this globally important disease. This review provides a comprehensive overview of the current issues surrounding how HbA 1c is measured and reported; and of the evidence for and against its use in diagnosis.

Original languageEnglish
Pages (from-to)227-236
Number of pages10
JournalJournal of Internal Medicine
Issue number3
Publication statusPublished or Issued - 1 Mar 2012
Externally publishedYes


  • Blood glucose
  • Diabetes mellitus
  • Diabetes mellitus - type 2
  • Diagnosis
  • Ethnic groups
  • Haemoglobin A - glycosylated

ASJC Scopus subject areas

  • Internal Medicine

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