Cross resistance between bacteriophages and colicins in Escherichia coli K 12

R. E.W. Hancock, J. K. Davies, P. Reeves

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Cross resistance between bacteriophages and colicins was studied using collections of bacteriophage and colicin resistant mutants of E. coli K 12. No new examples were found of highly specific one to one cross resistance of the type suggestive of common receptors. However, several groups of mutants showed tolerance to colicins and resistance to bacteriophages. Mutants known to be very defective in lipopolysaccharide composition were found to commonly show tolerance to certain colicins in addition to their bacteriophage resistance. Another group of mutants showed varying patterns of resistance to colicins E2, E3, K, L, .A, S4, N, and X and bacteriophages E4, K2, K20, K21, K29, and H+. However, many bacteriophage resistant mutants were fully colicin sensitive, and most colicin resistant mutants were fully sensitive to bacteriophages.

Original languageEnglish
Pages (from-to)1347-1350
Number of pages4
JournalJournal of Bacteriology
Volume126
Issue number3
DOIs
Publication statusPublished - 1 Jan 1976

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

Cite this