Cost-effectiveness of in vitro fertilization and embryo transfer

Ben W J Mol, Gouke J. Bonsel, John A. Collins, Maarten A H M Wiegerinck, Fulco Van Der Veen, Patrick M M Bossuyt

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Objective: Economic analyses in reproductive medicine often fail to take into account the chances of treatment-independent conception. We compared the cost-effectiveness of several realistic strategies involving IVF using no treatment as the reference strategy. Design: A decision tree was constructed for a subfertile couple in which the clinician had to decide whether to offer treatment with IVF. No treatment at all was used as the reference strategy.Setting: An analytic decision-making framework. Patient(s): Hypothetical subfertile couples. Intervention(s): Two potential treatment approaches: three IVF cycles performed as soon as possible, or no treatment performed initially and then three or four IVF cycles performed if a pregnancy resulting in a live birth does not occur naturally after 212 years. Main Outcome Measure(s): The cost of establishing one pregnancy that results in a live birth. Result(s): The cost-effectiveness of IVF depended not only on the costs and expected success rates of IVF itself but also on the couple-specific chances of treatment-independent conception. Consequently, the cost-effectiveness of IVF is strongly dependent on the age of the female partner. This finding corresponds with everyday clinical experience. Conclusion(s): Economic analyses in reproductive medicine should take into account the option of providing no treatment. Copyright (C) 2000 American Society for Reproductive Medicine.

LanguageEnglish
Pages748-754
Number of pages7
JournalFertility and Sterility
Volume73
Issue number4
DOIs
Publication statusPublished - 1 Apr 2000

Keywords

  • Cost-effectiveness
  • Economic analysis
  • IVF

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

Cite this

Mol, B. W. J., Bonsel, G. J., Collins, J. A., Wiegerinck, M. A. H. M., Van Der Veen, F., & Bossuyt, P. M. M. (2000). Cost-effectiveness of in vitro fertilization and embryo transfer. Fertility and Sterility, 73(4), 748-754. https://doi.org/10.1016/S0015-0282(99)00610-X
Mol, Ben W J ; Bonsel, Gouke J. ; Collins, John A. ; Wiegerinck, Maarten A H M ; Van Der Veen, Fulco ; Bossuyt, Patrick M M. / Cost-effectiveness of in vitro fertilization and embryo transfer. In: Fertility and Sterility. 2000 ; Vol. 73, No. 4. pp. 748-754.
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Mol, BWJ, Bonsel, GJ, Collins, JA, Wiegerinck, MAHM, Van Der Veen, F & Bossuyt, PMM 2000, 'Cost-effectiveness of in vitro fertilization and embryo transfer', Fertility and Sterility, vol. 73, no. 4, pp. 748-754. https://doi.org/10.1016/S0015-0282(99)00610-X

Cost-effectiveness of in vitro fertilization and embryo transfer. / Mol, Ben W J; Bonsel, Gouke J.; Collins, John A.; Wiegerinck, Maarten A H M; Van Der Veen, Fulco; Bossuyt, Patrick M M.

In: Fertility and Sterility, Vol. 73, No. 4, 01.04.2000, p. 748-754.

Research output: Contribution to journalArticle

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Mol BWJ, Bonsel GJ, Collins JA, Wiegerinck MAHM, Van Der Veen F, Bossuyt PMM. Cost-effectiveness of in vitro fertilization and embryo transfer. Fertility and Sterility. 2000 Apr 1;73(4):748-754. https://doi.org/10.1016/S0015-0282(99)00610-X