Conclusion: Human calorie restriction and anti-aging therapy

Arthur V. Everitt, Leonie Heilbronn, Brian J. Morris, Holly M. Brown-Borg, Brian J. Merry, Stephen J. Simpson, Krista A. Varady, Edward J. Masoro, Leanne M. Redman, David G. Le Couteur

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

During the twentieth century human life expectancy at birth increased by almost 30 years in developed countries and in the twenty-first century it is continuing to rise about 2 months in every year. Currently this is due mainly to medical advances reducing mortality from cardiovascular disease and cancer. In the twenty-first century the epidemic of obesity caused by overeating and reduced physical exercise is threatening to inhibit this continuing gain in human life expectancy. Life-long calorie restriction (CR) in the rat, mouse and the rhesus monkey retard aging, delay the onset of age-related diseases and significantly prolong life. Human 20% CR studies over 2-6 years reduce the risk factors for cardiovascular disease and diabetes. Okinawans, the longest-lived people on earth have been eating 20-40% less food than the Americans for half their life and live 4 years longer. Thus, calorie restriction has only a small impact on human life expectancy compared with the achievements of medicine, which continue to extend human life.

LanguageEnglish
Title of host publicationCalorie Restriction, Aging and Longevity
PublisherSpringer Netherlands
Pages311-318
Number of pages8
ISBN (Electronic)9789048185566
ISBN (Print)9789048185559
DOIs
Publication statusPublished - 1 Jan 2010
Externally publishedYes

Keywords

  • Calorie restriction
  • Cancer
  • Cardiovascular disease
  • Diabetes
  • Life expectancy
  • Obesity

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Everitt, A. V., Heilbronn, L., Morris, B. J., Brown-Borg, H. M., Merry, B. J., Simpson, S. J., ... Le Couteur, D. G. (2010). Conclusion: Human calorie restriction and anti-aging therapy. In Calorie Restriction, Aging and Longevity (pp. 311-318). Springer Netherlands. https://doi.org/10.1007/978-90-481-8556-6_18
Everitt, Arthur V. ; Heilbronn, Leonie ; Morris, Brian J. ; Brown-Borg, Holly M. ; Merry, Brian J. ; Simpson, Stephen J. ; Varady, Krista A. ; Masoro, Edward J. ; Redman, Leanne M. ; Le Couteur, David G. / Conclusion : Human calorie restriction and anti-aging therapy. Calorie Restriction, Aging and Longevity. Springer Netherlands, 2010. pp. 311-318
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Everitt, AV, Heilbronn, L, Morris, BJ, Brown-Borg, HM, Merry, BJ, Simpson, SJ, Varady, KA, Masoro, EJ, Redman, LM & Le Couteur, DG 2010, Conclusion: Human calorie restriction and anti-aging therapy. in Calorie Restriction, Aging and Longevity. Springer Netherlands, pp. 311-318. https://doi.org/10.1007/978-90-481-8556-6_18

Conclusion : Human calorie restriction and anti-aging therapy. / Everitt, Arthur V.; Heilbronn, Leonie; Morris, Brian J.; Brown-Borg, Holly M.; Merry, Brian J.; Simpson, Stephen J.; Varady, Krista A.; Masoro, Edward J.; Redman, Leanne M.; Le Couteur, David G.

Calorie Restriction, Aging and Longevity. Springer Netherlands, 2010. p. 311-318.

Research output: Chapter in Book/Report/Conference proceedingChapter

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AU - Simpson, Stephen J.

AU - Varady, Krista A.

AU - Masoro, Edward J.

AU - Redman, Leanne M.

AU - Le Couteur, David G.

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Everitt AV, Heilbronn L, Morris BJ, Brown-Borg HM, Merry BJ, Simpson SJ et al. Conclusion: Human calorie restriction and anti-aging therapy. In Calorie Restriction, Aging and Longevity. Springer Netherlands. 2010. p. 311-318 https://doi.org/10.1007/978-90-481-8556-6_18